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Despite its widespread use, the development of tools that help ensure high\u2010quality diagnostic outcomes from OCT systems has not kept pace with the technology's rapid advancements. In this work, a novel microstructure array phantom is presented capable of directly evaluating OCT sensitivity: its ability to distinguish meaningful signal from background noise. Through a combination of two\u2010photon direct laser writing (DLW) and thermally activated selective topographic equilibrium (TASTE), optically smooth microstructures are fabricated and shown to be effective in directly quantifying OCT sensitivity threshold, an advancement over the current practice of extrapolating system sensitivity in the high\u2010signal regime. This phantom serves as proof\u2010of\u2010concept for an easily disseminated regulatory science tool that will increase the consistency of performance reporting anywhere OCT is used. The advanced fabrication techniques used in this study also serve as demonstration of what future retinal phantoms could contain, helping to close the gap between the planar, largely two\u2010dimensional phantoms typically used for OCT systems and the geometrically complex, biomimetic phantoms common to other biomedical imaging modalities.<\/jats:p>","DOI":"10.1002\/admt.202401959","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T02:29:57Z","timestamp":1748226597000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tailored\u2010Reflectivity Microstructures for Measuring Signal Sensitivity of Optical Coherence Tomography Medical Imaging Systems"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9778-1912","authenticated-orcid":false,"given":"Declan M.","family":"Fitzgerald","sequence":"first","affiliation":[{"name":"Center for Devices and 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