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A computational DFT analysis of the palladium\u2010catalysed and the palladium\/ruthenium\u2010photocalysed mechanism for the functionalization of benzodiazepines indicated that, in the presence of the photocatalyst, the reaction proceeds via a low\u2010energy SET pathway avoiding the high\u2010energy oxidative addition step in the palladium\u2010only catalysed reaction pathway.<\/jats:p><jats:p><jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/adsc201700626-toc-0001-m.png\"><jats:alt-text>magnified image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text>\n<\/jats:p>","DOI":"10.1002\/adsc.201700626","type":"journal-article","created":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T21:48:13Z","timestamp":1499809693000},"page":"3261-3269","source":"Crossref","is-referenced-by-count":33,"title":["Combining 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