{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:56:05Z","timestamp":1791323765443,"version":"4.3.1"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T00:00:00Z","timestamp":1525219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["N_HKU715\/14"],"award-info":[{"award-number":["N_HKU715\/14"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Organic field\u2010effect transistors (OFETs)\u2010based sensors have a great potential to be integrated with the next generation smart surgical tools for monitoring different real\u2010time signals during surgery. However, allowing ultraflexible OFETs to have compatibility with standard medical sterilization procedures remains challenging. A novel capsule\u2010like OFET structure is demonstrated by utilizing the fluoropolymer CYTOP to serve both encapsulation and peeling\u2010off enhancement purposes. By adapting a thermally stable organic semiconductor, 2,10\u2010diphenylbis[1]benzothieno[2,3\u2010d;2\u2032,3\u2032\u2010d\u2032]naphtho[2,3\u2010b;6,7\u2010b\u2032]dithiophene (DPh\u2010BBTNDT), these devices show excellent stability in their electrical performance after sterilizing under boiling water and 100 \u00b0C\u2010saturated steam for 30 min. The ultrathin thickness (630 nm) enables the device to have superb mechanical flexibility with smallest bending radius down to 1.5 \u00b5m, which is essential for application on the highly tortuous medical catheter inside the human body. By immobilizing anti\u2010human C\u2010reactive protein (CRP) (an inflammation biomarker) monoclonal antibody on an extended gate of the OFET, a sensitivity for detecting CRP antigen down to 1 \u00b5g mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    can be achieved. An ecofriendly water floatation method realized by employing the wettability difference between CYTOP and polyacrylonitrile (PAN) can be used to transfer the device on a ventricular catheter, which successfully distinguishes an inflammatory patient from a healthy one.\n                  <\/jats:p>","DOI":"10.1002\/advs.201701053","type":"journal-article","created":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T07:26:33Z","timestamp":1525245993000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":71,"title":["Smart Surgical Catheter for C\u2010Reactive Protein Sensing Based on an Imperceptible Organic Transistor"],"prefix":"10.1002","volume":"5","author":[{"given":"Xudong","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering The University of Hong Kong  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengcheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pharmaceutical Biotechnology The University of Hong Kong  Hong Kong"},{"name":"Department of Medicine The University of Hong Kong  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Zhong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pharmaceutical Biotechnology The University of Hong Kong  Hong Kong"},{"name":"Department of Medicine The University of Hong Kong  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimin","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pharmaceutical Biotechnology The University of Hong Kong  Hong Kong"},{"name":"Department of Medicine The University of Hong Kong  Hong Kong"},{"name":"China Department of Pharmacology and Pharmacy The University of Hong Kong  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anderson C. 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