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Existing conformal soft bioelectrodes are applicable for basic electrocorticogram (ECoG) collecting\/monitoring. Nevertheless, as an emerging and promising approach, further multidisciplinary efforts are still demanded for in\u2010depth exploitations with these conformal soft electronics toward their practical neurophysiological applications in both scientific research and real\u2010world clinical operation. Here, clinically\u2010friendly silk\u2010supported\/delivered soft bioelectronics are developed, and multiple functions and features valuable for customizable intracranial applications (e.g., biocompatible and spontaneously conformal coupling with cortical surface, spatiotemporal ECoG detecting\/monitoring, electro\u2010neurophysiological neural stimulating\/decoding, controllable loading\/delivery of therapeutic molecules, and parallel optical readouts of operating states) are integrated.<\/jats:p>","DOI":"10.1002\/advs.201801617","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T06:25:09Z","timestamp":1551939909000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["Silk\u2010Enabled Conformal Multifunctional Bioelectronics for Investigation of Spatiotemporal Epileptiform Activities and Multimodal Neural 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