{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:12:41Z","timestamp":1789618361688,"version":"build-2803163510"},"reference-count":354,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T00:00:00Z","timestamp":1561075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2016YFC1100701"],"award-info":[{"award-number":["2016YFC1100701"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51873207"],"award-info":[{"award-number":["51873207"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51803006"],"award-info":[{"award-number":["51803006"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51673190"],"award-info":[{"award-number":["51673190"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51603204"],"award-info":[{"award-number":["51603204"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51673187"],"award-info":[{"award-number":["51673187"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51473165"],"award-info":[{"award-number":["51473165"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51520105004"],"award-info":[{"award-number":["51520105004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Immunotherapy has emerged as an effective strategy for the prevention and treatment of a variety of diseases, including cancer, infectious diseases, inflammatory diseases, and autoimmune diseases. Immunomodulatory nanosystems can readily improve the therapeutic effects and simultaneously overcome many obstacles facing the treatment method, such as inadequate immune stimulation, off\u2010target side effects, and bioactivity loss of immune agents during circulation. In recent years, researchers have continuously developed nanomaterials with new structures, properties, and functions. This Review provides the most recent advances of nanotechnology for immunostimulation and immunosuppression. In cancer immunotherapy, nanosystems play an essential role in immune cell activation and tumor microenvironment modulation, as well as combination with other antitumor approaches. In infectious diseases, many encouraging outcomes from using nanomaterial vaccines against viral and bacterial infections have been reported. In addition, nanoparticles also potentiate the effects of immunosuppressive immune cells for the treatment of inflammatory and autoimmune diseases. Finally, the challenges and prospects of applying nanotechnology to modulate immunotherapy are discussed.<\/jats:p>","DOI":"10.1002\/advs.201900101","type":"journal-article","created":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T03:46:41Z","timestamp":1561088801000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":325,"title":["Immunomodulatory Nanosystems"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7671-3144","authenticated-orcid":false,"given":"Xiangru","family":"Feng","sequence":"first","affiliation":[{"name":"Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 P. R. China"},{"name":"University of Science and Technology of China  Hefei 230026 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiguo","family":"Xu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongmin","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 P. R. China"},{"name":"Department of Gastrointestinal Colorectal and Anal Surgery China\u2013Japan Union Hospital of Jilin University  Changchun 130033 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wantong","family":"Song","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5232-8863","authenticated-orcid":false,"given":"Jianxun","family":"Ding","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3542-9256","authenticated-orcid":false,"given":"Xuesi","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,21]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1102-991"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.01.034"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3394"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2017.04.005"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12722"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00007"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7MD00158D"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8RA01690A"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.02.034"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.06.041"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC01371B"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.6b00747"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.12.006"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.7b02129"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.7b00950"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-018-2066-0"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8TB02491J"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b05893"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2008.11"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.04.005"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201600750"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1600299113"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-018-2124-7"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2018.07.004"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b01872"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.7b03218"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b02720"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8BM00190A"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2018.2624"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4PY01149J"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201800004"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201700821"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b00204"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03473-9"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201606036"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b01625"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b09041"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.10.047"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.07.057"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5TB02479J"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.16844"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI120923"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.05.018"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b02878"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.03.044"},{"key":"e_1_2_7_46_1","first-page":"1377","volume":"43","author":"Tsopelas C.","year":"2002","journal-title":"J. Nucl. Med."},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201701170"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2013.05.029"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.201700307"},{"key":"e_1_2_7_50_1","first-page":"13","volume":"32","author":"Jiang Z.","year":"2019","journal-title":"J. Funct. Polym."},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3BM60024F"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2016.12.070"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2017.03.201"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.04.020"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1039\/C2TB00063F"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b01071"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn5002112"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13193"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.19538"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3005"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.35.6_suppl.30"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.4161\/hv.29918"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2014.32.15_suppl.tps7608"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2017.01.007"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-11-430"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.3816\/CLC.2010.n.101"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-011-1003-3"},{"key":"e_1_2_7_68_1","first-page":"571","volume":"6","author":"DeGregorio M.","year":"2014","journal-title":"J. Thorac. Dis."},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv104"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70510-2"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.2174\/156800911793743664"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx711.030"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-10-156"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2015.1026529"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.34.15_suppl.e14578"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.09.018"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-11-246"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23810"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-0978"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-10-28"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.10.056"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-016-3751-x"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.2217\/lmt.14.43"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1136\/esmoopen-2016-000068"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-18-0198"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30254-7"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-015-1770-9"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-5193-9"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-018-2207-z"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2014.32.15_suppl.9050"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-015-1656-x"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2018.01.017"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1089\/nat.2018.0721"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201142361"},{"key":"e_1_2_7_95_1","doi-asserted-by":"crossref","first-page":"e20011","DOI":"10.1200\/jco.2013.31.15_suppl.e20011","volume":"31","author":"Romano E.","year":"2013","journal-title":"J. Clin. Oncol."},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.03.016"},{"key":"e_1_2_7_97_1","doi-asserted-by":"publisher","DOI":"10.1586\/erv.11.17"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MIB.0000437736.91712.a1"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000616"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2014.01.005"},{"key":"e_1_2_7_101_1","author":"Buhler S.","year":"2019","journal-title":"Rheumatology"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.09.069"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022273"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.07.039"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.10.036"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2018.02.005"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2013.0076"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2012.12.005"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1086\/513969"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2019.1578216"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw244"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0115126"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-184"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1102710"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01660"},{"key":"e_1_2_7_116_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007611"},{"key":"e_1_2_7_117_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0018559"},{"key":"e_1_2_7_118_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1808460115"},{"key":"e_1_2_7_119_1","doi-asserted-by":"publisher","DOI":"10.1086\/600120"},{"key":"e_1_2_7_120_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001937"},{"key":"e_1_2_7_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2016.25"},{"key":"e_1_2_7_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7258(94)90023-X"},{"key":"e_1_2_7_123_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2017-0208"},{"key":"e_1_2_7_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature18945"},{"key":"e_1_2_7_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2014.12.004"},{"key":"e_1_2_7_126_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201803001"},{"key":"e_1_2_7_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.97"},{"key":"e_1_2_7_128_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b04955"},{"key":"e_1_2_7_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-018-0146-7"},{"key":"e_1_2_7_130_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1441"},{"key":"e_1_2_7_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70333-4"},{"key":"e_1_2_7_132_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201606628"},{"key":"e_1_2_7_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.07.052"},{"key":"e_1_2_7_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.03.041"},{"key":"e_1_2_7_135_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4822"},{"key":"e_1_2_7_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.10.053"},{"key":"e_1_2_7_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12978"},{"key":"e_1_2_7_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.03.034"},{"key":"e_1_2_7_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2017.113"},{"key":"e_1_2_7_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2017.69"},{"key":"e_1_2_7_141_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2014.154"},{"key":"e_1_2_7_142_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201707112"},{"key":"e_1_2_7_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.01.044"},{"key":"e_1_2_7_144_1","first-page":"UNSP 0011","volume":"1","author":"Wang C.","year":"2017","journal-title":"Nat. Biomed. Eng."},{"key":"e_1_2_7_145_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201706098"},{"key":"e_1_2_7_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0236-8"},{"key":"e_1_2_7_147_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b02446"},{"key":"e_1_2_7_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.01.064"},{"key":"e_1_2_7_149_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn402145t"},{"key":"e_1_2_7_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2016.168"},{"key":"e_1_2_7_151_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-17-0981"},{"key":"e_1_2_7_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.04.010"},{"key":"e_1_2_7_153_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201802847"},{"key":"e_1_2_7_154_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn500216y"},{"key":"e_1_2_7_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01830-8"},{"key":"e_1_2_7_156_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.19987"},{"key":"e_1_2_7_157_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6NR09895A"},{"key":"e_1_2_7_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2017.54"},{"key":"e_1_2_7_159_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-017-0115-8"},{"key":"e_1_2_7_160_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b09112"},{"key":"e_1_2_7_161_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b00040"},{"key":"e_1_2_7_162_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b03568"},{"key":"e_1_2_7_163_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b03590"},{"key":"e_1_2_7_164_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802228"},{"key":"e_1_2_7_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.04.073"},{"key":"e_1_2_7_166_1","doi-asserted-by":"publisher","DOI":"10.1038\/32588"},{"key":"e_1_2_7_167_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1863"},{"key":"e_1_2_7_168_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines5010006"},{"key":"e_1_2_7_169_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.194.6.769"},{"key":"e_1_2_7_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.03.035"},{"key":"e_1_2_7_171_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0509541102"},{"key":"e_1_2_7_172_1","doi-asserted-by":"publisher","DOI":"10.4161\/hv.27449"},{"key":"e_1_2_7_173_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2006.01.006"},{"key":"e_1_2_7_174_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1332"},{"key":"e_1_2_7_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.08.023"},{"key":"e_1_2_7_176_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR06081H"},{"key":"e_1_2_7_177_1","first-page":"e34445","volume":"7","author":"Collins K. A.","year":"2017","journal-title":"Sci. Rep."},{"key":"e_1_2_7_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1523"},{"key":"e_1_2_7_179_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3001375"},{"key":"e_1_2_7_180_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b00978"},{"key":"e_1_2_7_181_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01911"},{"key":"e_1_2_7_182_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1601"},{"key":"e_1_2_7_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2011.05.016"},{"key":"e_1_2_7_184_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.02.024"},{"key":"e_1_2_7_185_1","doi-asserted-by":"publisher","DOI":"10.1021\/la203843m"},{"key":"e_1_2_7_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2008.10.004"},{"key":"e_1_2_7_187_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm869"},{"key":"e_1_2_7_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/82231"},{"key":"e_1_2_7_189_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn405520d"},{"key":"e_1_2_7_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.11.038"},{"key":"e_1_2_7_191_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0202-143"},{"key":"e_1_2_7_192_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1992.tb05481.x"},{"key":"e_1_2_7_193_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.2.453"},{"key":"e_1_2_7_194_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.6.2533"},{"key":"e_1_2_7_195_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00561-4"},{"key":"e_1_2_7_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2005.07.008"},{"key":"e_1_2_7_197_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2017.02.007"},{"key":"e_1_2_7_198_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2343"},{"key":"e_1_2_7_199_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2016-0197"},{"key":"e_1_2_7_200_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2008.04.001"},{"key":"e_1_2_7_201_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaf6843"},{"key":"e_1_2_7_202_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.09.017"},{"key":"e_1_2_7_203_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.2.762"},{"key":"e_1_2_7_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.03.014"},{"key":"e_1_2_7_205_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1937"},{"key":"e_1_2_7_206_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers6031670"},{"key":"e_1_2_7_207_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-018-0147-9"},{"key":"e_1_2_7_208_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201201470"},{"key":"e_1_2_7_209_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40824-018-0133-y"},{"key":"e_1_2_7_210_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1009010107"},{"key":"e_1_2_7_211_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.468967"},{"key":"e_1_2_7_212_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-05-0883"},{"key":"e_1_2_7_213_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2012.05.005"},{"key":"e_1_2_7_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.08.015"},{"key":"e_1_2_7_215_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15008"},{"key":"e_1_2_7_216_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1580"},{"key":"e_1_2_7_217_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.08.077"},{"key":"e_1_2_7_218_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31178"},{"key":"e_1_2_7_219_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.8b00460"},{"key":"e_1_2_7_220_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-15-0064"},{"key":"e_1_2_7_221_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.6b01432"},{"key":"e_1_2_7_222_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.107"},{"key":"e_1_2_7_223_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.207"},{"key":"e_1_2_7_224_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.03.036"},{"key":"e_1_2_7_225_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3380"},{"key":"e_1_2_7_226_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890201)63:3<604::AID-CNCR2820630334>3.0.CO;2-2"},{"key":"e_1_2_7_227_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201500089"},{"key":"e_1_2_7_228_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04605-x"},{"key":"e_1_2_7_229_1","doi-asserted-by":"publisher","DOI":"10.1586\/era.12.101"},{"key":"e_1_2_7_230_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-12-617159"},{"key":"e_1_2_7_231_1","first-page":"908","volume":"123","author":"Boulaftali Y.","year":"2013","journal-title":"J. Clin. Invest."},{"key":"e_1_2_7_232_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06655-7"},{"key":"e_1_2_7_233_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja2010175"},{"key":"e_1_2_7_234_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201706320"},{"key":"e_1_2_7_235_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-011-1047-x"},{"key":"e_1_2_7_236_1","doi-asserted-by":"publisher","DOI":"10.1586\/eci.10.81"},{"key":"e_1_2_7_237_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201800678"},{"key":"e_1_2_7_238_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8140(93)90179-C"},{"key":"e_1_2_7_239_1","doi-asserted-by":"publisher","DOI":"10.1667\/RR13495.1"},{"key":"e_1_2_7_240_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112824"},{"key":"e_1_2_7_241_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2012.00090"},{"key":"e_1_2_7_242_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3958"},{"key":"e_1_2_7_243_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1367"},{"key":"e_1_2_7_244_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201604139"},{"key":"e_1_2_7_245_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2016-0306"},{"key":"e_1_2_7_246_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5NH00064E"},{"key":"e_1_2_7_247_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02725-4"},{"key":"e_1_2_7_248_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep44839"},{"key":"e_1_2_7_249_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.13.8"},{"key":"e_1_2_7_250_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00109"},{"key":"e_1_2_7_251_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b08025"},{"key":"e_1_2_7_252_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl404560v"},{"key":"e_1_2_7_253_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802233"},{"key":"e_1_2_7_254_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.11.048"},{"key":"e_1_2_7_255_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aat9120"},{"key":"e_1_2_7_256_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2016.09.001"},{"key":"e_1_2_7_257_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1805713115"},{"key":"e_1_2_7_258_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.01.041"},{"key":"e_1_2_7_259_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2013.254"},{"key":"e_1_2_7_260_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201505231"},{"key":"e_1_2_7_261_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201701644"},{"key":"e_1_2_7_262_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl504798g"},{"key":"e_1_2_7_263_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2016.02.010"},{"key":"e_1_2_7_264_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199905280-00001"},{"key":"e_1_2_7_265_1","doi-asserted-by":"publisher","DOI":"10.1086\/427192"},{"key":"e_1_2_7_266_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12510"},{"key":"e_1_2_7_267_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201706759"},{"key":"e_1_2_7_268_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.04.078"},{"key":"e_1_2_7_269_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4529"},{"key":"e_1_2_7_270_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2017.10.002"},{"key":"e_1_2_7_271_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)91352-1"},{"key":"e_1_2_7_272_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1502850112"},{"key":"e_1_2_7_273_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature02759"},{"key":"e_1_2_7_274_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2012.08.002"},{"key":"e_1_2_7_275_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201701395"},{"key":"e_1_2_7_276_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2013.04.014"},{"key":"e_1_2_7_277_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20051782"},{"key":"e_1_2_7_278_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc500108b"},{"key":"e_1_2_7_279_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.10.034"},{"key":"e_1_2_7_280_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.11.43"},{"key":"e_1_2_7_281_1","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1128\/iai.59.3.1153-1161.1991","volume":"59","author":"O'Hanley P.","year":"1991","journal-title":"Infect. Immun."},{"key":"e_1_2_7_282_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(01)00139-X"},{"key":"e_1_2_7_283_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2013.54"},{"key":"e_1_2_7_284_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201701366"},{"key":"e_1_2_7_285_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00131-11"},{"key":"e_1_2_7_286_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00031-09"},{"key":"e_1_2_7_287_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.04.071"},{"key":"e_1_2_7_288_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-00193-w"},{"key":"e_1_2_7_289_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a015487"},{"key":"e_1_2_7_290_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.57.2.3"},{"key":"e_1_2_7_291_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2013.10.005"},{"key":"e_1_2_7_292_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm804"},{"key":"e_1_2_7_293_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2009.00206.x"},{"key":"e_1_2_7_294_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2011.01941.x"},{"key":"e_1_2_7_295_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b01385"},{"key":"e_1_2_7_296_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1806908115"},{"key":"e_1_2_7_297_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.6b04130"},{"key":"e_1_2_7_298_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjy181"},{"key":"e_1_2_7_299_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.06.015"},{"key":"e_1_2_7_300_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b02226"},{"key":"e_1_2_7_301_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2016.04.001"},{"key":"e_1_2_7_302_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201800510"},{"key":"e_1_2_7_303_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1408686111"},{"key":"e_1_2_7_304_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00281"},{"key":"e_1_2_7_305_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2017.12.010"},{"key":"e_1_2_7_306_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.03.015"},{"key":"e_1_2_7_307_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature16962"},{"key":"e_1_2_7_308_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.04.003"},{"key":"e_1_2_7_309_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12034"},{"key":"e_1_2_7_310_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.8879"},{"key":"e_1_2_7_311_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b09107"},{"key":"e_1_2_7_312_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b00087"},{"key":"e_1_2_7_313_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S5495"},{"key":"e_1_2_7_314_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2009.09.010"},{"key":"e_1_2_7_315_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.08.010"},{"key":"e_1_2_7_316_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.180.5.1961"},{"key":"e_1_2_7_317_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21316"},{"key":"e_1_2_7_318_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1219852110"},{"key":"e_1_2_7_319_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2016.10.041"},{"key":"e_1_2_7_320_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4157"},{"key":"e_1_2_7_321_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.05.009"},{"key":"e_1_2_7_322_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12909"},{"key":"e_1_2_7_323_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.03.018"},{"key":"e_1_2_7_324_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.155.3.1151"},{"key":"e_1_2_7_325_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano1010031"},{"key":"e_1_2_7_326_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2011.05.013"},{"key":"e_1_2_7_327_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.178"},{"key":"e_1_2_7_328_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328346d47d"},{"key":"e_1_2_7_329_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2013.00245"},{"key":"e_1_2_7_330_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23961"},{"key":"e_1_2_7_331_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198108063050603"},{"key":"e_1_2_7_332_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.149.3.758"},{"key":"e_1_2_7_333_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2012.167"},{"key":"e_1_2_7_334_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.07.116"},{"key":"e_1_2_7_335_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2017.56"},{"key":"e_1_2_7_336_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.276329"},{"key":"e_1_2_7_337_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.194.5.629"},{"key":"e_1_2_7_338_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-018-0091-8"},{"key":"e_1_2_7_339_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature18300"},{"key":"e_1_2_7_340_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtnano.2019.100029"},{"key":"e_1_2_7_341_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2013.07.011"},{"key":"e_1_2_7_342_1","first-page":"246012","volume":"2015","author":"Beyth N.","year":"2015","journal-title":"J. Evidence\u2010Based Complementary Altern. Med."},{"key":"e_1_2_7_343_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0805532107"},{"key":"e_1_2_7_344_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn405724x"},{"key":"e_1_2_7_345_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.04.060"},{"key":"e_1_2_7_346_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.04.005"},{"key":"e_1_2_7_347_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.06.001"},{"key":"e_1_2_7_348_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(97)00131-2"},{"key":"e_1_2_7_349_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3330"},{"key":"e_1_2_7_350_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b02340"},{"key":"e_1_2_7_351_1","first-page":"UNSP 0029","volume":"1","author":"Jiang W.","year":"2017","journal-title":"Nat. Biomed. Eng."},{"key":"e_1_2_7_352_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.04.063"},{"key":"e_1_2_7_353_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat3775"},{"key":"e_1_2_7_354_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.09.050"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fadvs.201900101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.201900101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/advs.201900101","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.201900101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T08:52:54Z","timestamp":1759740774000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.201900101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,21]]},"references-count":354,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1002\/advs.201900101"],"URL":"https:\/\/doi.org\/10.1002\/advs.201900101","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,21]]},"assertion":[{"value":"2019-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1900101"}}