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Additionally, satisfactory bone\u2010implant integration is another important indicator of an ideal implant. Here, an antibiotic\u2010free antibacterial nanofilm based on oxide perovskite\u2010type calcium titanate (CTO)\/fibrous red phosphorus (RP) on titanium implant surface (Ti\u2010CTO\/RP) in which the P\u2013N heterojunction and internal electric field are established at the heterointerface, is designed. Near\u2010infrared light\u2010excited electron\u2013hole pairs are effectively separated and transferred through the synergism of the internal electric field and band offset, which strongly boosts the photocatalytic eradication of MRSA biofilms by reactive oxygen species with an efficacy of 99.42% \u00b1 0.22% in vivo. Additionally, the charge transfer endows the heterostructure with hyperthermia to assist biofilm eradication. Furthermore, CTO\/RP nanofilm provides a superior biocompatible and osteoconductive platform that enables the proliferation and osteogenic differentiation of mesenchymal stem cells, thus contributing to the subsequent implant\u2010to\u2010bone osseointegration after eradicating MRSA biofilms.<\/jats:p>","DOI":"10.1002\/advs.202002211","type":"journal-article","created":{"date-parts":[[2021,6,19]],"date-time":"2021-06-19T04:44:35Z","timestamp":1624077875000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Enhanced Near\u2010Infrared Photocatalytic Eradication of MRSA Biofilms and Osseointegration Using Oxide Perovskite\u2010Based P\u2013N Heterojunction"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0499-3674","authenticated-orcid":false,"given":"Congyang","family":"Mao","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology Li Ka Shing Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong 999077 China"},{"name":"Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma Department of Orthopaedics and Traumatology The University of Hong Kong\u2010Shenzhen Hospital  Shenzhen 518053 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Biomedical Materials Engineering Research Center Collaborative Innovation Center for Advanced Organic Chemical Materials Co\u2010constructed by the Province and Ministry Hubei Key Laboratory of Polymer Materials Ministry\u2010of\u2010Education Key Laboratory for the Green Preparation and Application of Functional Materials School of Materials Science and Engineering Hubei University  Wuhan 430062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology Li Ka Shing Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong 999077 China"},{"name":"Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma Department of Orthopaedics and Traumatology The University of Hong Kong\u2010Shenzhen Hospital  Shenzhen 518053 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhou","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology Li Ka Shing Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong 999077 China"},{"name":"Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma Department of Orthopaedics and Traumatology The University of Hong Kong\u2010Shenzhen Hospital  Shenzhen 518053 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology Li Ka Shing Faculty of Medicine The University of Hong Kong  Pokfulam Hong Kong 999077 China"},{"name":"Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma Department of Orthopaedics and Traumatology The University of Hong Kong\u2010Shenzhen Hospital  Shenzhen 518053 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangmei","family":"Liu","sequence":"additional","affiliation":[{"name":"Biomedical Materials Engineering Research Center Collaborative Innovation Center for Advanced Organic Chemical Materials Co\u2010constructed by the Province and Ministry Hubei Key Laboratory of Polymer Materials Ministry\u2010of\u2010Education Key Laboratory for the Green Preparation and Application of Functional Materials School of Materials Science and Engineering Hubei University  Wuhan 430062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuilin","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering the Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China Tianjin University  Tianjin 300072 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth M. 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