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The effectiveness of conventional locally\u2010administered medications against diseases affecting these oral milieus may be compromised by constant salivary flow. For systemically\u2010administered medications, drug resistance and adverse side\u2010effects are issues that need to be resolved. New strategies for drug delivery have been investigated over the last decade to overcome these obstacles. Synthesis of nanoparticle\u2010containing agents that promote healing represents a quantum leap in ensuring safe, efficient drug delivery to the affected tissues. Micro\/nanoencapsulants with unique structures and properties function as more favorable drug\u2010release platforms than conventional treatment approaches. The present review provides an overview of newly\u2010developed nanocarriers and discusses their potential applications and limitations in various fields of dentistry and oral medicine.<\/jats:p>","DOI":"10.1002\/advs.202004014","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T03:01:49Z","timestamp":1612753309000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":186,"title":["Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2456-0961","authenticated-orcid":false,"given":"Pooyan","family":"Makvandi","sequence":"first","affiliation":[{"name":"Chemistry Department, Faculty of Science Shahid Chamran University of Ahvaz  Ahvaz 6153753843 Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uros","family":"Josic","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences University of Bologna  Via San Vitale 59 Bologna 40125 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Delfi","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences University of Naples \u201cFederico II\u201d  Complesso Universitario Monte S. 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