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Although numerous physical barriers such as balloon or hydrogel are developed for the prevention of IUAs, the therapeutic efficacy is barely satisfactory due to limited endometrial healing, which may lead to recurrence. Herein, a second near\u2010infrared (NIR\u2010II) light\u2010responsive shape memory composite based on the combination of cuprorivaite (CaCuSi\n                    <jats:sub>4<\/jats:sub>\n                    O\n                    <jats:sub>10<\/jats:sub>\n                    ) nanosheets (CUP NSs) as photothermal conversion agents and polymer poly(\n                    <jats:sc>d<\/jats:sc>\n                    ,\n                    <jats:sc>l<\/jats:sc>\n                    \u2010lactide\u2010\n                    <jats:italic>co<\/jats:italic>\n                    \u2010trimethylene carbonate) (PT) as shape memory building blocks is developed. The as\u2010prepared CUP\/PT composite possesses excellent shape memory performance under NIR\u2010II light, and the improved operational feasibility as an antiadhesion barrier for the treatment of IUAs. Moreover, the released ions (Cu, Si) can stimulate the endometrial regeneration due to the angiogenic bioactivity. This study provides a new strategy to prevent IUA and restore the injured endometrium relied on shape memory composite with enhanced tissues reconstruction ability.\n                  <\/jats:p>","DOI":"10.1002\/advs.202102220","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T08:25:06Z","timestamp":1645863906000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Bioactive NIR\u2010II Light\u2010Responsive Shape Memory Composite Based on Cuprorivaite Nanosheets for Endometrial Regeneration"],"prefix":"10.1002","volume":"9","author":[{"given":"Chenle","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology The First Affiliated Hospital of Wenzhou Medical University  Wenzhou Zhejiang 325000 China"},{"name":"Department of Obstetrics and Gynecology Shenzhen University General Hospital Clinical Medical Academy Shenzhen University  Shenzhen 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