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A quenched photosensitizer (\u201coff\u201d state) is developed and escorted into a tumor\u2010targeting oxaliplatin\u2010embedded micelle. Once reaching the tumor cell, the micelle is clasped to release free oxaliplatin, as well as the \u201coff\u201d photosensitizer, which is further activated (\u201cturned\u2010on\u201d) in the tumor reducing microenvironment to provide optical imaging and photothermal effect. 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