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Despite strict limits (e.g., 50 parts per billion (ppb) in the European Union), routine monitoring of benzene is rarely done since low\u2010cost sensors lack accuracy. This work presents a compact, battery\u2010driven device that detects benzene in gas mixtures with unprecedented selectivity (&gt;200) over inorganics, ketones, aldehydes, alcohols, and even challenging toluene and xylene. This can be attributed to strong Lewis acid sites on a packed bed of catalytic WO<jats:sub>3<\/jats:sub> nanoparticles that prescreen a chemoresistive Pd\/SnO<jats:sub>2<\/jats:sub> sensor. That way, benzene is detected down to 13 ppb with superior robustness to relative humidity (RH, 10\u201380%), fulfilling the strictest legal limits. As proof of concept, benzene is quantified in indoor air in good agreement (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> \u2265 0.94) with mass spectrometry. This device is readily applicable for personal exposure assessment and can assist the implementation of low\u2010emission zones for sustainable environments.<\/jats:p>","DOI":"10.1002\/advs.202103853","type":"journal-article","created":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T06:38:02Z","timestamp":1637995082000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Handheld Device for Selective Benzene Sensing over Toluene and Xylene"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2251-4753","authenticated-orcid":false,"given":"Ines C.","family":"Weber","sequence":"first","affiliation":[{"name":"Particle Technology Laboratory Department of Mechanical and Process Engineering ETH Zurich  Zurich CH\u20108092 Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"R\u00fcedi","sequence":"additional","affiliation":[{"name":"Particle 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