{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T11:28:53Z","timestamp":1771500533752,"version":"3.50.1"},"reference-count":145,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81903117"],"award-info":[{"award-number":["81903117"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102830"],"award-info":[{"award-number":["82102830"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81972843"],"award-info":[{"award-number":["81972843"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81120108017"],"award-info":[{"award-number":["81120108017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Polyploidization and depolyploidization are critical processes in the normal development and tissue homeostasis of diploid organisms. Recent investigations have revealed that polyaneuploid cancer cells (PACCs) exploit this ploidy variation as a survival strategy against anticancer treatment and for the repopulation of tumors. Unscheduled polyploidization and chromosomal instability in PACCs enhance malignancy and treatment resistance. However, their inability to undergo mitosis causes catastrophic cellular death in most PACCs. Adaptive ploid reversal mechanisms, such as multipolar mitosis, centrosome clustering, meiosis\u2010like division, and amitosis, counteract this lethal outcome and drive cancer relapse. The purpose of this work is to focus on PACCs induced by cytotoxic therapy, highlighting the latest discoveries in ploidy dynamics in physiological and pathological contexts. Specifically, by emphasizing the role of \u201cpoly\u2010depolyploidization\u201d in tumor progression, the aim is to identify novel therapeutic targets or paradigms for combating diseases associated with aberrant ploidies.<\/jats:p>","DOI":"10.1002\/advs.202306318","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T08:26:43Z","timestamp":1713342403000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Surviving the Storm: The Role of Poly\u2010 and Depolyploidization in Tissues and Tumors"],"prefix":"10.1002","volume":"11","author":[{"given":"Yucui","family":"Zhao","sequence":"first","affiliation":[{"name":"Cancer Center Shanghai General Hospital Shanghai Jiao Tong University School of Medicine  Shanghai 201620 China"},{"name":"Department of Radiation Oncology Second Affiliated Hospital Zhejiang University School of Medicine  Hangzhou 310009 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sijia","family":"He","sequence":"additional","affiliation":[{"name":"Cancer Center Shanghai General Hospital Shanghai Jiao Tong University School of Medicine  Shanghai 201620 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minghui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Cancer Center Shanghai General Hospital Shanghai Jiao Tong University School of Medicine  Shanghai 201620 China"},{"name":"Department of Radiation Oncology First Affiliated Hospital of Nanjing Medical University  Nanjing 210029 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4474-3848","authenticated-orcid":false,"given":"Qian","family":"Huang","sequence":"additional","affiliation":[{"name":"Cancer Center Shanghai General Hospital Shanghai Jiao Tong University School of Medicine  Shanghai 201620 China"},{"name":"Shanghai Key Laboratory of Pancreatic Diseases Shanghai General Hospital Shanghai Jiao Tong University School of Medicine  Shanghai 201620 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2013.01.003"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09414"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.11.014"},{"key":"e_1_2_7_2_3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-20916-y"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-00321-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-14286-0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2021.07.009"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23384-6"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0165-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1689-y"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-03133-3"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-21-2065"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-020-00299-4"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2023.08.004"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2020838118"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acr.2020.03.001"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.724781"},{"key":"e_1_2_7_11_3","doi-asserted-by":"publisher","DOI":"10.1002\/1878-0261.12913"},{"key":"e_1_2_7_11_4","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-022-02588-0"},{"key":"e_1_2_7_11_5","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2316436"},{"key":"e_1_2_7_11_6","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-21-2342"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001112"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202204177"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-019-0044-1"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adf7195"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-19-0264"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2017.78"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2013.96"},{"key":"e_1_2_7_16_3","first-page":"132","author":"Liu J.","year":"2021","journal-title":"Semin. Cancer Biol."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/eva.12929"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.157115"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a040881"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15125"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.adk4276"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2021.04.005"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-017-0040-0"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2018.10.005"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-33110-5"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg.2017.26"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-13-0285"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-020-0584-7"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05082-5"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-019-0171-x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2019.10.009"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-019-0437-8"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b19906"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.156034"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2019.09.002"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2173"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgv050"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v11.i3.121"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559-020-01367-y"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2018.02.006"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03753-4"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3756"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001597"},{"key":"e_1_2_7_42_1","first-page":"1","volume":"32","author":"Wenzel E. S.","year":"2018","journal-title":"In Vivo"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.03.016"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.12.036"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.01.031"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2017.04.004"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2011.12.019"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-03-634402"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2014.12.015"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2021.07.001"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2020.03.009"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2020.09.007"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-018-0201-8"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.4161\/15384101.2015.945831"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41374-018-0157-x"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-018-0084-6"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan6490"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-021-00436-9"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-57127-0_5"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2017.04.010"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26309"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.11.008"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-312623"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2121-6-6"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200403014"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2022.04.005"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e16-05-0268"},{"key":"e_1_2_7_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw612"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.06.029"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.289728.116"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-04578-4"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201745440"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellbi.2005.10.008"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2022.05.007"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm4025"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-015-2305-6"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax4199"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.07.042"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-318021"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E22-07-0296"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14020442"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201704102"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2019.07.018"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-3364"},{"key":"e_1_2_7_77_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.26251"},{"key":"e_1_2_7_77_3","doi-asserted-by":"publisher","DOI":"10.3390\/genes10020083"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2021.05.017"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2009.05.011"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-1535"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.02.012"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/oncsis.2016.75"},{"key":"e_1_2_7_83_1","first-page":"1","volume":"2016","author":"Zhang S.","year":"2016","journal-title":"Stem Cells Int"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-05758-6"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1420702111"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-18-0619"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-018-0249-2"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.3.2.663"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-13-151"},{"key":"e_1_2_7_89_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10399"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-017-2587-9"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2019.11.002"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.03.009"},{"key":"e_1_2_7_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2018.09.001"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2017.72"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-1861"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21447-2"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2023113510"},{"key":"e_1_2_7_97_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-19-0987"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-0164"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-018-0683-z"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2019.100941"},{"key":"e_1_2_7_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.01.056"},{"key":"e_1_2_7_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.09.085"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST20190034"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2013.09.012"},{"key":"e_1_2_7_103_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8020225"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm501179r"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026619666190227222930"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M092247"},{"key":"e_1_2_7_106_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2960"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1224922"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.08.027"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2018.1463947"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202152509"},{"key":"e_1_2_7_110_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf8399"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.02.025"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06464-z"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-022-00467-x"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-023-00699-5"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2023-4482"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.202306318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T20:54:53Z","timestamp":1759784093000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.202306318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,17]]},"references-count":145,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/advs.202306318"],"URL":"https:\/\/doi.org\/10.1002\/advs.202306318","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,17]]},"assertion":[{"value":"2023-09-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2306318"}}