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In this study, an artificial Q\u2010grader comprising surface\u2010engineered zinc oxide (ZnO) thin films is developed as the artificial nose, tongue, and AI\u2010based statistical data analysis as the artificial brain for identifying both aroma and flavor chemicals in coffee beans. A poly(vinylidene fluoride\u2010co\u2010hexafluoropropylene)\/ZnO thin film transistor (TFT)\u2010based liquid sensor is the artificial tongue, and an Au, Ag, or Pd nanoparticles\/ZnO nanohybrid gas sensor is the artificial nose. In order to classify the flavor of coffee beans (acetic acid (sourness), ethyl butyrate and 2\u2010furanmethanol (sweetness), caffeine (bitterness)) and the origin of coffee beans (Papua New Guinea, Brazil, Ethiopia, and Colombia\u2010decaffeine), rational combination of TFT transfer and dynamic response curves capture the liquids and gases\u2010dependent electrical transport behavior and principal component analysis (PCA)\u2010assisted machine learning (ML) is implemented. A PCA\u2010assisted ML model distinguished the four target flavors with &gt;92% prediction accuracy. ML\u2010based regression model predicts the flavor chemical concentrations with &gt;99% accuracy. Also, the classification model successfully distinguished four different types of coffee\u2010bean with 100% accuracy.<\/jats:p>","DOI":"10.1002\/advs.202308976","type":"journal-article","created":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T20:04:20Z","timestamp":1712433860000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Artificial Q\u2010Grader: Machine Learning\u2010Enabled Intelligent Olfactory and Gustatory Sensing System"],"prefix":"10.1002","volume":"11","author":[{"given":"Moonjeong","family":"Jang","sequence":"first","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"},{"name":"National Nano Fab Center (NNFC)  Daejeon 34141 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garam","family":"Bae","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"},{"name":"Department of Medical Artificial Intelligence Konyang University  Daejeon 35365 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeong Min","family":"Kwon","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hee","family":"Cho","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do Hyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saewon","family":"Kang","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soonmin","family":"Yim","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung","family":"Myung","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongsun","family":"Lim","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Sook","family":"Lee","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0487-2055","authenticated-orcid":false,"given":"Wooseok","family":"Song","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"},{"name":"School of Electronic and Electrical Engineering Sunkyunkwan University  Suwon 16419 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki\u2010Seok","family":"An","sequence":"additional","affiliation":[{"name":"Thin Film Materials Research Center Korea Research Institute of Chemical Technology  Daejeon 34114 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,6]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42256-021-00360-9"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2NR04551F"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/aisy.202100194"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1149\/2754-2726\/acbe0c"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.7b00620"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.7b00496"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0045-y"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.8b00937"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202106017"},{"key":"e_1_2_8_10_1","first-page":"104","volume":"4","author":"Tan J.","year":"2020","journal-title":"Artif. 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