{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:36:13Z","timestamp":1790883373814,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["FutureFellowshipgrant(FT200100939)"],"award-info":[{"award-number":["FutureFellowshipgrant(FT200100939)"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["Discoverygrant(DP190101864)"],"award-info":[{"award-number":["Discoverygrant(DP190101864)"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000995","name":"Australian National University","doi-asserted-by":"publisher","award":["Our Health in Our Hands (OHIOH)"],"award-info":[{"award-number":["Our Health in Our Hands (OHIOH)"]}],"id":[{"id":"10.13039\/501100000995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000995","name":"Australian National University","doi-asserted-by":"publisher","award":["a strategic initiative"],"award-info":[{"award-number":["a strategic initiative"]}],"id":[{"id":"10.13039\/501100000995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diabetic ketoacidosis (DKA) is a life\u2010threatening acute complication of diabetes characterized by the accumulation of ketone bodies in the blood. Breath acetone, a ketone, directly correlates with blood ketones. Therefore, monitoring breath acetone can significantly enhance the safety and efficacy of diabetes care. In this work, the design and fabrication of an InP\/Pt\/chitosan nanowire array\u2010based chemiresistive acetone sensor is reported. By incorporation of chitosan as a surface\u2010functional layer and a Pt Schottky contact for efficient charge transfer processes and photovoltaic effect, self\u2010powered, highly selective acetone sensing is achieved. The sensor has exhibited an ultra\u2010wide acetone detection range from sub\u2010ppb to &gt;100\u2009000\u00a0ppm level at room temperature, covering those in the exhaled breath from healthy individuals (300\u2013800\u00a0ppb) to people at high risk of DKA (&gt;75\u00a0ppm). The nanowire sensor has also been successfully integrated into a handheld breath testing prototype, the Ketowhistle, which can successfully detect different ranges of acetone concentrations in\u00a0simulated breath samples. The Ketowhistle demonstrates the immediate potential for non\u2010invasive ketone monitoring for people living with diabetes, in particular for DKA prevention.<\/jats:p>","DOI":"10.1002\/advs.202309481","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T06:54:12Z","timestamp":1710312852000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Nanowire Array Breath Acetone Sensor for Diabetes Monitoring"],"prefix":"10.1002","volume":"11","author":[{"given":"Shiyu","family":"Wei","sequence":"first","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Li","sequence":"additional","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnan","family":"Murugappan","sequence":"additional","affiliation":[{"name":"Commonwealth Scientific and Industrial Research Organisation (CSIRO) Mineral Resources  Private Bag 10 Clayton South VIC 3169 Australia"},{"name":"Nanotechnology Research Laboratory Research School of Chemistry College of Science The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyuan","family":"Li","sequence":"additional","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mykhaylo","family":"Lysevych","sequence":"additional","affiliation":[{"name":"Australian National Fabrication Facility The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushal","family":"Vora","sequence":"additional","affiliation":[{"name":"Australian National Fabrication Facility The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hark Hoe","family":"Tan","sequence":"additional","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chennupati","family":"Jagadish","sequence":"additional","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buddini I","family":"Karawdeniya","sequence":"additional","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J","family":"Nolan","sequence":"additional","affiliation":[{"name":"School of Medicine and Psychology College of Health and Medicine The Australian National University  Canberra ACT 2600 Australia"},{"name":"Department of Diabetes and Endocrinology The Canberra Hospital  Garran ACT 2605 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Tricoli","sequence":"additional","affiliation":[{"name":"Nanotechnology Research Laboratory Research School of Chemistry College of Science The Australian National University  Canberra ACT 2600 Australia"},{"name":"Nanotechnology Research Laboratory Faculty of Engineering The University of Sydney  Camperdown 2006 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9070-8373","authenticated-orcid":false,"given":"Lan","family":"Fu","sequence":"additional","affiliation":[{"name":"Australian Research Council Centre of Excellence for Transformative Meta\u2010Optical Systems Department of Electronic Materials Engineering Research School of Physics The Australian National University  Canberra ACT 2600 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,13]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.1c00312"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.7861\/clinmed.2019-0284"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2021.102275"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-7560(199911\/12)15:6<412::AID-DMRR72>3.0.CO;2-8"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/s21144902"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0321-x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios11010026"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296815572366"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-014-8401-8"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21242"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2020.128104"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr300174a"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2016.05.013"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3410\/M2-56"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001503"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202104958"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202104416"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b00673"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/a827347z"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsanm.0c03345"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b16258"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceramint.2016.06.145"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c01063"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202107596"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202207199"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.116690"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7TB00787F"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2010.05.001"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2012.11.063"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl500704r"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/pip.3083"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10854-009-9996-y"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1230969"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2006.05.023"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/50.5.415"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b08778"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.200700784"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics8010012"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2021.129823"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b01284"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/chemosensors11050288"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2015.05.068"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8MH01365A"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtnano.2019.100058"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/s21155153"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics9040224"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.516"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mssp.2022.106897"},{"key":"e_1_2_8_39_3","doi-asserted-by":"publisher","DOI":"10.1088\/1752-7163\/ac4916"},{"key":"e_1_2_8_39_4","doi-asserted-by":"publisher","DOI":"10.3390\/bios11120476"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc15-1380"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201600797"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202000377"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2015.0202"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.202309481","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.202309481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T21:17:05Z","timestamp":1759958225000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.202309481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,13]]},"references-count":54,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/advs.202309481"],"URL":"https:\/\/doi.org\/10.1002\/advs.202309481","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,13]]},"assertion":[{"value":"2023-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2309481"}}