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Current mechanical assistive devices, such as intra\u2010aortic balloon pumps (IABP) and extracorporeal membrane oxygenation (ECMO), offer temporary stabilization but are limited to short\u2010term use due to risks associated with prolonged blood contact. This research presents a novel proof\u2010of\u2010concept soft robotic device designed with the aim of achieving low\u2010risk, medium\u2010term counterpulsation therapy. The device employs a nature\u2010inspired growing mechanism for potentially minimally invasive deployment around the ascending aorta, coupled with hydraulic artificial muscles for aortic compression. It demonstrated a maximum stroke volume of 16.48 \u00b1 0.21 mL (SD, n = 5), outperforming all other non\u2010pneumatic extra\u2010aortic devices. 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These findings highlight the device's strong potential for optimization as a promising solution to improve outcomes for hemodynamically unstable HF\u00a0patients.<\/jats:p>","DOI":"10.1002\/advs.202412120","type":"journal-article","created":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T02:39:11Z","timestamp":1735353551000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Development of a Self\u2010Deploying Extra\u2010Aortic Compression Device for Medium\u2010Term Hemodynamic Stabilization: A Feasibility Study"],"prefix":"10.1002","volume":"12","author":[{"given":"Adrienne","family":"Ji","sequence":"first","affiliation":[{"name":"Graduate School of Biomedical Engineering, Faculty of Engineering, and Tyree Institute of Health Engineering (IHealthE) UNSW Sydney  Kensington Campus Sydney NSW 2052 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