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To address this issue, a new analytical pipeline named\n                    <jats:italic>FREQuency\u2010resolved Network Estimation<\/jats:italic>\n                    via\n                    <jats:italic>Source Separation<\/jats:italic>\n                    (FREQ\u2010NESS) is introduced. This pipeline is designed to estimate the activation and spatial configuration of simultaneous brain networks across frequencies by analyzing the frequency\u2010resolved multivariate covariance between whole\u2010brain voxel time series. In this study, FREQ\u2010NESS is applied to source\u2010reconstructed magnetoencephalography (MEG) data during resting state and isochronous auditory stimulation. Our results reveal simultaneous, frequency\u2010specific brain networks during resting state, such as the default mode, alpha\u2010band, and motor\u2010beta networks. During auditory stimulation, FREQ\u2010NESS detects: 1) emergence of networks attuned to the stimulation frequency, 2) spatial reorganization of existing networks, such as alpha\u2010band networks shifting from occipital to sensorimotor areas, 3) stability of networks unaffected by auditory stimuli. Furthermore, auditory stimulation significantly enhances cross\u2010frequency coupling, with the phase of auditory networks attuned to the stimulation modulating gamma band amplitude in medial temporal lobe networks. In conclusion, FREQ\u2010NESS effectively maps the brain's spatiotemporal dynamics, providing a comprehensive view of brain function by revealing a landscape of simultaneous, frequency\u2010resolved networks and their interaction.\n                  <\/jats:p>","DOI":"10.1002\/advs.202413195","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T01:55:22Z","timestamp":1744336522000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["FREQ\u2010NESS Reveals the Dynamic Reconfiguration of Frequency\u2010Resolved Brain Networks During Auditory Stimulation"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2349-1386","authenticated-orcid":false,"given":"Mattia","family":"Rosso","sequence":"first","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"},{"name":"IPEM Institute for Systematic Musicology Ghent University  Ghent 9000 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Fern\u00e1ndez\u2010Rubio","sequence":"additional","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Erik","family":"Keller","sequence":"additional","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"},{"name":"MARCS Institute for Brain, Behaviour and Development Western Sydney University  Sydney 2751 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira","family":"Brattico","sequence":"additional","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"},{"name":"Department of Education, Psychology, Communication University of Bari Aldo Moro  Bari 70121 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vuust","sequence":"additional","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten L","family":"Kringelbach","sequence":"additional","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"},{"name":"Centre for Eudaimonia and Human Flourishing Linacre College University of Oxford  Oxford OX39BX United\u00a0Kingdom"},{"name":"Department of Psychiatry University of Oxford  Oxford OX37JX United\u00a0Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9983-3819","authenticated-orcid":false,"given":"Leonardo","family":"Bonetti","sequence":"additional","affiliation":[{"name":"Center for Music in the Brain Department of Clinical Medicine Aarhus University &amp; The Royal Academy of Music  Aarhus\/Aalborg Aarhus 8000 Denmark"},{"name":"Centre for Eudaimonia and Human Flourishing Linacre College University of Oxford  Oxford OX39BX United\u00a0Kingdom"},{"name":"Department of Psychiatry University of Oxford  Oxford OX37JX United\u00a0Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"e_1_2_10_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3963"},{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.03.023"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.09.038"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.10.002"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2017.141"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3063"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.11.034"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1154735"},{"key":"e_1_2_10_9_1","first-page":"1","author":"Hancock F.","year":"2024","journal-title":"Nat. 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