{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:27:29Z","timestamp":1788780449197,"version":"build-2803163510"},"reference-count":82,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100015650","name":"Fundaci\u00f3n Carolina","doi-asserted-by":"publisher","award":["Doctorado 2020"],"award-info":[{"award-number":["Doctorado 2020"]}],"id":[{"id":"10.13039\/501100015650","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["PID2021\u2010124795NB\u2010I00"],"award-info":[{"award-number":["PID2021\u2010124795NB\u2010I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Prussian\u2010blue nanoparticles (PBNPs) show promise in electrochemical hydrogen peroxide (H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    ) sensing but face operational stability challenges without complex strategies. This study introduces a simplified, polymer\u2010based synthesis method, enhancing their stability in a single step. Chemical polymerization of Prussian\u2010blue (PB) and poly(3,4\u2010ethylenedioxythiophene) (PEDOT) with gelatin as a polycationic soft template yields a self\u2010assembled PB\u2010infused Catalytic Hetero\u2010interface Architecture (PB\u2010CHIA) that remarkably improves the stability of PBNPs and offers functional groups for enzyme immobilization, supporting robust biosensing applications. The softened PEDOT rigidity extends PB\u2010CHIA's applicability to various carbonaceous electrode substrates, including glassy carbon and laser\u2010induced graphene (LIG) via simple drop\u2010casting. A fluidic cell module designed with the optimized LIG morphology (nano\u2010fibrous fringes, LIG\u2010F, diameter: 72.87\u00a0\u00b1\u00a012.24\u00a0nm) modified with PB\u2010CHIA and glucose oxidase enables non\u2010invasive urine glucose monitoring. The configuration accurately quantifies glucose within a linear range of 10\u2013400\u00a0\u00b5M [R\n                    <jats:sup>2<\/jats:sup>\n                    : 0.991, Sensitivity: 29.88 \u00b1 4.98\u00a0\u00b5A\u00a0mM\u207b\u00b9\u00a0cm\u207b\n                    <jats:sup>2<\/jats:sup>\n                    , Detection Limit: 4.52 \u00b1 2.24\u00a0\u00b5M], covering medical needs. A near\u2010field communication potentiostat is devised for a fully integrated, batteryless, wireless point\u2010of\u2010care (POC) prototype, enabling rapid smartphone readouts in 15\u00a0s for daily home\u2010based use. The stable operation of PB\u2010CHIA allows working electrodes\u2019 scalable production, highlighting its potential for diverse POC devices in urinary analysis reliant on H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    assays.\n                  <\/jats:p>","DOI":"10.1002\/advs.202500365","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T17:13:50Z","timestamp":1741713230000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Prussian\u2010Blue Catalysis and NFC Synergy: a Battery\u2010Free Laser\u2010Induced Graphene\u2010Based Platform for Urine Glucose Monitoring at Point\u2010of\u2010Care"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3459-7525","authenticated-orcid":false,"given":"Sinan","family":"Uzun\u00e7ar","sequence":"first","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and BIST  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Environmental Engineering Department Engineering Faculty Zonguldak B\u00fclent Ecevit University  Zonguldak 67100 Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8921-4205","authenticated-orcid":false,"given":"Gabriel","family":"Maroli","sequence":"additional","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and BIST  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Instituto de Investigaciones en Ingenier\u00eda El\u00e9ctrica Alfredo Desages (IIIE) Universidad Nacional del Sur  Bah\u00eda Blanca 8000 Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6083-833X","authenticated-orcid":false,"given":"Massimo","family":"Urban","sequence":"additional","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and BIST  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Facultad de Biociencias Universitat Aut\u00f2noma de Barcelona  Campus de la UAB, Bellaterra Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2486-8085","authenticated-orcid":false,"given":"Arben","family":"Merko\u00e7i","sequence":"additional","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and BIST  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Catalan Institution for Research and Advanced Studies (ICREA)  Passeig de Llu\u00eds Companys, 23 Barcelona 08010 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,6]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41378-021-00302-w"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2023.115103"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-009-1560-z"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2002.31425"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.510"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02218.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep39372"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asems.2022.100016"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2021.130046"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2022.131459"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsanm.1c04220"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.btre.2014.06.003"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2004.02.003"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1AY00676B"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4109(200106)13:10<813::AID-ELAN813>3.0.CO;2-Z"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11427-019-1570-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/137577a0"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2004.12.001"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.260"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coelec.2017.07.006"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202108616"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.200600033"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202104234"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsanm.3c01199"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2481(99)00010-7"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.16.795"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0956-5663(96)89084-1"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0956-5663(02)00169-0"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/elan.200390021"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2006.11.020"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep06891"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA24128J"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.1c01200"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.electacta.2010.06.036"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-5394(01)00146-3"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelechem.2012.04.005"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA07800J"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/b609548h"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/elan.200804408"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/la0344128"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/1556-276X-7-1"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.20964\/2017.05.57"},{"key":"e_1_2_9_43_1","first-page":"26","author":"Uzun\u00e7ar S.","year":"2021","journal-title":"Mater. Today Commun."},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1149\/1945-7111\/ac131c"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2021.338664"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2022.123841"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mser.2020.100546"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201500305"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202370019"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202205292"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b05223"},{"key":"e_1_2_9_52_1","volume":"9","author":"Nie S.","year":"2021","journal-title":"Front. Chem."},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.synthmet.2014.10.008"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/0379-6779(94)02465-B"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1039\/c3dt50823d"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1RA09084D"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf9031603"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2012.05.017"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2017.09.068"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.1c00085"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.0c01259"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.synthmet.2011.04.024"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b04616"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2022.114851"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2008.10.010"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.synthmet.2018.11.022"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mser.2022.100681"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn202020w"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0013-4686(00)00354-6"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0TC02402C"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.7b10582"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5TA04578A"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2016.11.126"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112725"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.6b00247"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.10.5.622"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25-S007"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2024.116421"},{"key":"e_1_2_9_79_1","volume-title":"Glucosuria","author":"Cowart S. L.","year":"1990"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4LC00163J"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/elan.200302761"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.2c05438"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.202500365","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/advs.202500365","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.202500365","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T10:13:37Z","timestamp":1771323217000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.202500365"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,6]]},"references-count":82,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/advs.202500365"],"URL":"https:\/\/doi.org\/10.1002\/advs.202500365","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,6]]},"assertion":[{"value":"2025-01-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2500365"}}