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While polysomnography (PSG) remains the gold standard for diagnosis, its clinical application is limited by high costs, complex setup requirements, and sleep quality interference. Although wearable devices using photoplethysmography (PPG) have shown promise in SAS detection, their continuous operation demands substantial power consumption, hindering long\u2010term monitoring capabilities. Here, a dual\u2010modal wearable system is presented integrating a piezoelectric nanogenerator (PENG) and PPG sensor with a biomimetic fingertip structure for SAS detection. A two\u2010stage detection strategy is adopted where the self\u2010powered PENG performs continuous preliminary screening, activating the PPG sensor only when suspicious events are detected. Combined with a Vision Transformer\u2010based deep learning model, the high\u2010accuracy configuration achieves 99.59% accuracy, while the low\u2010power two\u2010stage approach maintained 94.95% accuracy. This dual\u2010modal wearable pulse detection system provides a practical solution for long\u2010term SAS monitoring, overcoming the limitations of traditional PSG while maintaining high detection accuracy. The system's versatility in both home and clinical settings offers the potential for improving early detection rates and treatment outcomes for SAS patients.<\/jats:p>","DOI":"10.1002\/advs.202501750","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T11:10:24Z","timestamp":1745925024000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A Dual\u2010Modal Wearable Pulse Detection System Integrated with Deep Learning for High\u2010Accuracy and Low\u2010Power Sleep Apnea Monitoring"],"prefix":"10.1002","volume":"12","author":[{"given":"Jia","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Cardiology Beijing Hospital National Center of Gerontology Institute of Geriatric Medicine Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing 100730 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangtao","family":"Xue","sequence":"additional","affiliation":[{"name":"Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences  Beijing 101400 China"},{"name":"School of Medical Technology Beijing Institute of Technology  Beijing 100081 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2918-2488","authenticated-orcid":false,"given":"Yang","family":"Zou","sequence":"additional","affiliation":[{"name":"Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences  Beijing 101400 China"},{"name":"School of Medical Technology Beijing Institute of Technology  Beijing 100081 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Hospital National Center of Gerontology Institute of Geriatric Medicine Chinese Academy of Medical Sciences &amp; Peking University Fifth School of Clinical Medicine  Beijing 100730 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhan","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Computer Science and Suzhou Institute for Advanced Research University of Science and Technology of China  Hefei Anhui 230026 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medcine Beijing Hospital National Center of Gerontology Institute of Geriatric Medicine Chinese Academy of Medical Sciences  Beijing 100730 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medcine Beijing Hospital National Center of Gerontology Institute of Geriatric Medicine Chinese Academy of Medical Sciences  Beijing 100730 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqian","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences  Beijing 101400 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Xing","sequence":"additional","affiliation":[{"name":"School of Computer Science and Suzhou Institute for Advanced Research University of Science and Technology of China  Hefei Anhui 230026 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences  Beijing 101400 China"},{"name":"School of Nanoscience and Technology University of Chinese Academy of Sciences  Beijing 100049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Hospital National Center of Gerontology Institute of Geriatric Medicine Chinese Academy of Medical Sciences &amp; 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