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However, most current devices are primarily designed to track physiological signals and physical indicators, which limits their ability to assess a comprehensive range of health parameters during exercise. Therefore, there is a need for a multimodal wearable platform that can capture diverse exercise\u2010related metrics. Here, a wireless soft athlete bioelectronic system is presented that monitors various physiological signals and metabolites during exercise. This system includes a smart\u2010sensing lip guard that detects ventilated carbon dioxide, osmolality, environmental conditions, and humidity\u2014key indicators of the metabolites expelled from the nose and mouth. Additionally, the cardiac patch complements the lip guard by monitoring multiple signals, such as electrocardiograms, heart rates, temperature, and motion. This integrated system is capable of detecting exercise\u2010induced conditions such as dehydration, hyperventilation, and abnormal heart signals. By combining data from both physiological and environmental factors, the wearable device offers a comprehensive assessment of how external conditions influence an athlete's performance. Evaluating the device with human subjects under varying temperature conditions demonstrates its effectiveness in observing exercise performance, regardless of environmental factors, highlighting its significant potential for enhancing athlete healthcare and performance monitoring.<\/jats:p>","DOI":"10.1002\/advs.202503880","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T09:44:17Z","timestamp":1750412657000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Wireless Soft Athlete Bioelectronics for Monitoring Carbon Dioxide Ventilation and Physiological Performance"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7242-4502","authenticated-orcid":false,"given":"Tae Woog","family":"Kang","sequence":"first","affiliation":[{"name":"George W. 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Woodruff School of Mechanical Engineering College of Engineering Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4159-5966","authenticated-orcid":false,"given":"Yoon Jae","family":"Lee","sequence":"additional","affiliation":[{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"School of Electrical and Computer Engineering Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0439-6236","authenticated-orcid":false,"given":"Hodam","family":"Kim","sequence":"additional","affiliation":[{"name":"George W. Woodruff School of Mechanical Engineering College of Engineering Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4082-0786","authenticated-orcid":false,"given":"Sung Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4456-2761","authenticated-orcid":false,"given":"Youngjin","family":"Kwon","sequence":"additional","affiliation":[{"name":"George W. Woodruff School of Mechanical Engineering College of Engineering Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"School of Materials Science and Engineering Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4951-3168","authenticated-orcid":false,"given":"Hoon","family":"Yi","sequence":"additional","affiliation":[{"name":"George W. 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Woodruff School of Mechanical Engineering College of Engineering Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1706-5030","authenticated-orcid":false,"given":"Hyeonseok","family":"Kim","sequence":"additional","affiliation":[{"name":"Wearable Intelligent Systems and Healthcare Center (WISH Center) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7916-3612","authenticated-orcid":false,"given":"Alec","family":"Harp","sequence":"additional","affiliation":[{"name":"School of Biological Sciences Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0094-3450","authenticated-orcid":false,"given":"Jud","family":"Ready","sequence":"additional","affiliation":[{"name":"Electro\u2010Optical Systems Laboratory Georgia Tech Research Institute  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2944-1494","authenticated-orcid":false,"given":"Melinda","family":"Millard\u2010Stafford","sequence":"additional","affiliation":[{"name":"School of Biological Sciences Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5526-3882","authenticated-orcid":false,"given":"Woon\u2010Hong","family":"Yeo","sequence":"additional","affiliation":[{"name":"George W. 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Petit Institute for Bioengineering and Biosciences Georgia Institute of Technology  Atlanta GA 30332 USA"},{"name":"Korea KIAT\u2010Georgia Tech Semiconductor Electronics Center (K\u2010GTSEC) Institute for Matter and Systems Georgia Institute of Technology  Atlanta GA 30332 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202404211"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c17939"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202403238"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22020573"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1012-3"},{"key":"e_1_2_9_6_1","volume":"7","author":"Xu C.","year":"2024","journal-title":"Nat. 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