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While research often focuses on venous blood analysis, menstruation blood is an overlooked but promising source. Evidence shows a strong correlation between biomarker levels in menstruation and venous blood for many clinical analytes. A wearable, microfluidic monitoring platform integrated into hygiene pads is presented for electronic\u2010free, naked\u2010eye detection of disease biomarkers in menstruation blood (MenstruAI). Semi\u2010quantitative detection of C\u2010reactive protein (CRP), cancer biomarkers carcinoembryonic antigen (CEA) and cancer antigen 125 (CA\u2010125), and endometriosis biomarker CA\u2010125 is demonstrated. The biomarker\u2010induced color changes can be read by the naked eye or a smartphone app with a machine\u2010learning algorithm for semi\u2010quantitative analysis. MenstruAI can revolutionize women's health by offering a non\u2010invasive, affordable, and accessible health monitoring method, democratizing healthcare, and enhancing service availability and equity.<\/jats:p>","DOI":"10.1002\/advs.202505170","type":"journal-article","created":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T07:08:19Z","timestamp":1748070499000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A Wearable In\u2010Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood"],"prefix":"10.1002","volume":"12","author":[{"given":"Lucas","family":"Dosnon","sequence":"first","affiliation":[{"name":"Nanoparticle Systems Engineering Laboratory Institute of Energy and Process Engineering (IEPE) Department of Mechanical and Process Engineering (D\u2010MAVT) ETH Zurich  Sonneggstrasse 3 Zurich 8092 Switzerland"},{"name":"Particles Biology Interactions Laboratory Department of Materials 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