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However, the sluggish charge\u2010transfer rate and restricted active sites of the nanozymes lead to poor enzyme\u2010like activity and further impede their biomimetic catalysis. Herein, a three\u2010channel electron\u2010engineered Fe\u201088A@CeO\n                    <jats:sub>2<\/jats:sub>\n                    \/carbon dots (Fe\u201088A@CeO\n                    <jats:sub>2<\/jats:sub>\n                    \/CDs) nanozyme is proposed for efficient biomimetic catalysis. Fe\u201088A@CeO\n                    <jats:sub>2<\/jats:sub>\n                    \/CDs nanozyme is prepared by incorporation of CeO\n                    <jats:sub>2<\/jats:sub>\n                    and CDs into the porosity of Fe\u201088A. Specifically, the original Fe (II)\/Fe (III) and the introduced Ce (III)\/Ce (IV) redox couples of the nanozyme constitute a dual electron transfer channel. Furthermore, the presence of CDs produces another electron transfer channel. The three\u2010channel electron engineering strategy for nanozymes can accelerate the electron transfer process accompanied with more active sites, thereby greatly enhancing the oxidase\u2010like activity of Fe\u201088A@CeO\n                    <jats:sub>2<\/jats:sub>\n                    \/CDs for biomimetic catalysis. The nanozyme can efficiently convert oxygen to \u00b7, oxidizing colorless 3,3\u2032,5,5\u2032\u2010tetramethylbenzidine (TMB) to blue ox\u2010TMB, and meanwhile the ox\u2010TMB effectively quenches the fluorescence of CDs. As proof of concept, the nanozyme is utilized to construct a colorimetric\u2010fluorescence bimodal immunosensor for monitoring Staphylococcal enterotoxin B with excellent performance. This work provides promising insight into designing excellent nanozymes for effective biomimetic catalysis in various fields.\n                  <\/jats:p>","DOI":"10.1002\/advs.202509713","type":"journal-article","created":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T17:23:13Z","timestamp":1756660993000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Three\u2010Channel Electron Engineered Fe\u201088A@CeO\n                    <sub>2<\/sub>\n                    \/CDs Nanozyme with Enhanced Oxidase\u2010Like Activity for Efficient Biomimetic Catalysis"],"prefix":"10.1002","volume":"12","author":[{"given":"Kai","family":"Liu","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering Yangzhou University  Yangzhou 225002 P.R. 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