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To address this challenge, 3D oxygen vacancy (OV)\u2010rich iron\u2010doped Bi\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    S (Fe\u2010Bi\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2\u2010X<\/jats:sub>\n                    S, Fe\u2010BOS) nanoflowers (NFs) are synthesized for the first time via an ion\u2010exchange method. The resulting material exhibits a small band gap, abundant OVs, and favorable charge\u2010transfer properties. It also shows robust photothermal performance and strong photocatalytic reactive oxygen species (ROS)\u2010generation ability. Fe\u2010BOS@C\/H Gel is subsequently prepared by crosslinking hydrazide\u2010modified chondroitin sulfate, the Fe\u2010BOS NFs, and oxidized hyaluronic acid via a dynamic Schiff reaction. 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This study provides an innovative solution that utilizes the synergistic strategy of \u201clight\u2010driven antibacterial performance and pro\u2010regeneration\u201d to treat drug\u2010resistant bacterial\u2010infected wounds.\n                  <\/jats:p>","DOI":"10.1002\/advs.202518215","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T07:27:59Z","timestamp":1767598079000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["NIR Light\u2010Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration"],"prefix":"10.1002","volume":"13","author":[{"given":"Dong","family":"Mo","sequence":"first","affiliation":[{"name":"Department of Biotherapy Cancer Center and State Key Laboratory of Biotherapy West China Hospital Sichuan University  Chengdu 610041 China"},{"name":"Department of Radiology Chongqing General Hospital Chongqing University  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