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This review establishes a comprehensive framework for material design by delineating critical requirements, including optical clarity, mechanical anisotropy, and stable wet adhesion within dynamic ocular environments. The performances of natural, synthetic, and decellularized\u2010matrix hydrogels are systematically compared to elucidate the structure\u2013property relationships essential for recapitulating native corneal physiology. Beyond passive substitution, the transition toward bioactive regeneration is examined through analyses of scarless wound healing, sustained drug delivery, and stimuli\u2010responsive implants. Furthermore, the integration of advanced technologies is evaluated with a focus on three\u2010\/four\u2010dimensional bioprinting for hierarchical architectural reconstruction and hydrogel\u2010based wearable bioelectronics for real\u2010time sensing. 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