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Piezoelectric biomaterials offer a route to address this challenge, yet the potential to harness ambient oral motions (e.g., mastication) as a continuous power source for autonomous therapeutic action remains largely unexplored. Here, we report a motion\u2010activated smart dental implant abutment (SDIA) constructed from a toughened piezoelectric composite comprising a 3D interconnected barium titanate (BaTiO\n                    <jats:sub>3<\/jats:sub>\n                    ) ceramic framework infiltrated with a high\u2010strength polymer matrix. This architecture imparts exceptional flexural strength and fracture toughness via polymer\u2010mediated crack deflection. Under simulated oral pressure, the SDIA demonstrates efficient biomechanical\u2010to\u2010electrical energy conversion, driving a potent piezo\u2010catalytic effect that generates sufficient reactive oxygen species (ROS) to eradicate 96.5% of\n                    <jats:italic>E. coli<\/jats:italic>\n                    and 89.7% of\n                    <jats:italic>S. aureus<\/jats:italic>\n                    , and robustly inhibits biofilm formation. Concurrently, the motion\u2010induced electrical cues directly modulate fibroblast behavior by upregulating the MAPK and PI3K\u2010Akt signaling pathways, substantially enhancing cell adhesion and proliferation. This work establishes a new paradigm for smart biomaterials, demonstrating that harnessing natural physiological motion can power autonomous implants capable of delivering synergistic antibacterial and regenerative therapies to prevent clinical device failure.\n                  <\/jats:p>","DOI":"10.1002\/advs.202523944","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T14:31:52Z","timestamp":1779805912000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Oral Motion\u2010Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect"],"prefix":"10.1002","volume":"13","author":[{"given":"Xiyu","family":"Shi","sequence":"first","affiliation":[{"name":"Department of Dental Materials &amp; Dental Medical Devices Testing Center Peking University School and Hospital of Stomatology  Beijing P. R. 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