{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:55:05Z","timestamp":1790603705453,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"54","license":[{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Drug misuse and abuse remain critical global challenges, driving public health and societal burdens through increased morbidity and mortality, impaired driving, interpersonal violence, and escalating healthcare and criminal\u2010justice expenditures. Drug\u2010facilitated sexual assault (DFSA) remains a pressing societal concern, and \u03b3\u2010hydroxybutyrate (GHB) is a representative DFSA agent categorized as a date rape drug. GHB is endogenously derived, exists at low concentrations, and has a short detection window and weak optical features that complicate conventional assays and contribute to missed or delayed detection. These challenges are especially important because GHB can induce rapid clinical presentation that overlaps with alcohol or other sedatives, making timely identification critical for acute management and safeguarding decisions. This necessitates reliable detection of exogenous GHB in minimally invasive samples. This study presents a graphene\u2010based electrical biosensor for rapid detection of GHB with high sensitivity and selectivity, achieving a limit of detection (LOD) of 100\u00a0f\n                    <jats:sc>m<\/jats:sc>\n                    for standard GHB solutions and a correlated LOD of 100\u00a0f\n                    <jats:sc>m<\/jats:sc>\n                    in artificial urine matrices. The platform enables rapid, on\u2010site detection with concentration\u2010dependent electrical responses across a wide dynamic range suitable for clinically and forensically relevant GHB levels, with broad implications for diagnostics, forensic analysis, and public health strategies to reduce drug\u2010related harm.\n                  <\/jats:p>","DOI":"10.1002\/advs.76399","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T16:13:51Z","timestamp":1783354431000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Immediate\u2010Response Detection System for \u03b3\u2010Hydroxybutyrate to Enhance Personal Safety in Social Environments"],"prefix":"10.1002","volume":"13","author":[{"given":"Jai Eun","family":"An","sequence":"first","affiliation":[{"name":"Interdisciplinary Program in Bioengineering Seoul National University  Seoul Republic of Korea"},{"name":"SKKU Advanced Institute of Nanotechnology (SAINT) Sungkyunkwan University  Suwon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisung","family":"Kwak","sequence":"additional","affiliation":[{"name":"Nanophotonic System Research Center Korea Institute of Science and Technology (KIST)  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"SKKU Advanced Institute of Nanotechnology (SAINT) Sungkyunkwan University  Suwon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaeeun","family":"Kim","sequence":"additional","affiliation":[{"name":"Nanophotonic System Research Center Korea Institute of Science and Technology (KIST)  Seoul Republic of Korea"},{"name":"KU\u2010KIST Graduate School of Converging Science and Technology Korea University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Eun","family":"Seo","sequence":"additional","affiliation":[{"name":"SKKU Advanced Institute of Nanotechnology (SAINT) Sungkyunkwan University  Suwon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3735-7727","authenticated-orcid":false,"given":"Nathaniel S.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Interdisciplinary Program in Bioengineering Seoul National University  Seoul Republic of Korea"},{"name":"School of Chemical and Biological Engineering Institute of Chemical Processes  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3222-4231","authenticated-orcid":false,"given":"Yong\u2010Sang","family":"Ryu","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering Korea University  Seoul Republic of Korea"},{"name":"Department of Micro\/Nano Systems Korea University  Seoul Republic of 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