{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T10:28:08Z","timestamp":1787221688034,"version":"build-2736575974"},"reference-count":90,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Natural products remain vital sources of therapeutics, particularly anti\u2010infectives, and members of the phylum\n                    <jats:italic>Myxococcota<\/jats:italic>\n                    constitute an especially rich reservoir for their discovery. Based on decades of microbiological efforts, we present 154 new\n                    <jats:italic>Myxococcota<\/jats:italic>\n                    genomes and propose a revised taxonomy expanding the number of described families from 11 to 28 and genera from 32 to 90. Comparison with an equivalent set from the prime source\n                    <jats:italic>Actinomycetota<\/jats:italic>\n                    shows that\n                    <jats:italic>Myxococcota<\/jats:italic>\n                    possess a comparable biosynthetic diversity, underscoring their promise for large\u2010scale isolation and sequencing efforts. The vast untapped potential reflected in 2,387 uncharacterized gene cluster families is highlighted by genome mining efforts, yielding four validated compounds exhibiting novel chemistry, including myxolutamids and myxopentacins. We show that many\n                    <jats:italic>Myxococcota<\/jats:italic>\n                    \u2010derived natural products, such as myxolutamid A and two new sorangicin derivatives, are conserved within taxonomic lineages. New described families thus bear high biosynthetic potential underpinning\u00a0the\u00a0importance of precise taxonomic classification guiding targeted drug discovery. To facilitate community access and exploration of these data, we provide ABC\u2010Myxo (\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/tools.helmholtz-hips.de\/abc_myxo\/\">https:\/\/tools.helmholtz\u2010hips.de\/abc_myxo\/<\/jats:ext-link>\n                    ), an interactive web\u2010based atlas of\n                    <jats:italic>Myxococcota<\/jats:italic>\n                    biosynthetic gene clusters.\n                  <\/jats:p>","DOI":"10.1002\/advs.76919","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T11:51:23Z","timestamp":1786017083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum\n                    <i>Myxococcota<\/i>"],"prefix":"10.1002","author":[{"given":"Amay Ajaykumar","family":"Agrawal","sequence":"first","affiliation":[{"name":"Research Group Drug Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"Center For Bioinformatics Saarland University  Saarbr\u00fccken Germany"},{"name":"Graduate School of Computer Science Saarland University  Saarbr\u00fccken Saarland Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"German Center for Infection Research (DZIF) Partner Site Hannover\u2010Braunschweig  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyi","family":"Chen","sequence":"additional","affiliation":[{"name":"Research Group Drug Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"Center For Bioinformatics Saarland University  Saarbr\u00fccken Germany"},{"name":"Graduate School of Computer Science Saarland University  Saarbr\u00fccken Saarland Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal D.","family":"Bader","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"PharmaScienceHub  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"MyxoTech GmbH  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Popoff","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Krug","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Walesch","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia","family":"Oueis","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haowen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim J.","family":"Hug","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Keller","sequence":"additional","affiliation":[{"name":"Research Group Drug Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Hirsch","sequence":"additional","affiliation":[{"name":"Chair For Clinical Bioinformatics Center for Bioinformatics Saarland University Saarland University Campus  Saarland Germany"},{"name":"Department of Clinical Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azat","family":"Tagirdzhanov","sequence":"additional","affiliation":[{"name":"Center For Bioinformatics Saarland University  Saarbr\u00fccken Germany"},{"name":"Research Group Human\u2010Microbe Systems Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Malygina","sequence":"additional","affiliation":[{"name":"Research Group Drug Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Victory E.","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"Department of Biology Far Eastern University  Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey","family":"Gurevich","sequence":"additional","affiliation":[{"name":"Center For Bioinformatics Saarland University  Saarbr\u00fccken Germany"},{"name":"PharmaScienceHub  Saarbr\u00fccken Germany"},{"name":"Research Group Human\u2010Microbe Systems Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"Department of Computer Science Saarland University  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4598-634X","authenticated-orcid":false,"given":"Judith","family":"Boldt","sequence":"additional","affiliation":[{"name":"German Center for Infection Research (DZIF) Partner Site Hannover\u2010Braunschweig  Braunschweig Germany"},{"name":"Leibniz Institute DSMZ \u2013 German Collection of Microorganisms and Cell Cultures  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyke","family":"Bunk","sequence":"additional","affiliation":[{"name":"Leibniz Institute DSMZ \u2013 German Collection of Microorganisms and Cell Cultures  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Overmann","sequence":"additional","affiliation":[{"name":"German Center for Infection Research (DZIF) Partner Site Hannover\u2010Braunschweig  Braunschweig Germany"},{"name":"Leibniz Institute DSMZ \u2013 German Collection of Microorganisms and Cell Cultures  Braunschweig Germany"},{"name":"Institute of Microbiology Technical University  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3131-1656","authenticated-orcid":false,"given":"Ulrich","family":"N\u00fcbel","sequence":"additional","affiliation":[{"name":"German Center for Infection Research (DZIF) Partner Site Hannover\u2010Braunschweig  Braunschweig Germany"},{"name":"Leibniz Institute DSMZ \u2013 German Collection of Microorganisms and Cell Cultures  Braunschweig Germany"},{"name":"Institute of Microbiology Technical University  Braunschweig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Keller","sequence":"additional","affiliation":[{"name":"Chair For Clinical Bioinformatics Center for Bioinformatics Saarland University Saarland University Campus  Saarland Germany"},{"name":"Department of Clinical Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9445-477X","authenticated-orcid":false,"given":"Olga V.","family":"Kalinina","sequence":"additional","affiliation":[{"name":"Research Group Drug Bioinformatics Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"Center For Bioinformatics Saarland University  Saarbr\u00fccken Germany"},{"name":"PharmaScienceHub  Saarbr\u00fccken Germany"},{"name":"Medical Faculty Saarland University  Homburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Microbial Natural Products Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Centre for Infection Research (HZI)  Saarbr\u00fccken Germany"},{"name":"German Center for Infection Research (DZIF) Partner Site Hannover\u2010Braunschweig  Braunschweig Germany"},{"name":"PharmaScienceHub  Saarbr\u00fccken Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01706\u201021"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/b901287g"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/c001260m"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6NP00106H"},{"key":"e_1_2_8_6_1","first-page":"1059","article-title":"Myxococcales Tchan, Portion and Prevot 1948, 398^<AI>","volume":"2","author":"Reichenbach H. O. V.","year":"2005","journal-title":"Bergey's Manual of Systematic Bacteriology"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/0\u2010387\u201030747\u20108_3"},{"key":"e_1_2_8_8_1","first-page":"59","volume-title":"Methods in Enzymology","author":"Garcia R. O.","year":"2009"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.006943"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-39044-9_303"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evaa212"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1227206"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00012\u201021"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms6030084"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/md16090303"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b01285"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanmic.2024.07.010"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202256033"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780195150667.001.0001"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201705913"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201021848\u20103"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44386\u2010025\u201000020\u20107"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.38.145"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2NP00012A"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-211-78207-1"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2011.02.022"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC06919A"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2024.04.019"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202104484"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.3c00063"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8SC01325J"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010021\u201007955\u2010x"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.761869"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1189"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201003184\u20101"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-39044-9_308"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-39044-9_271"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-39044-9_305"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.01688\u201014"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02147\u201024"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9102143"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713\u201030\u20101\u2010135"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2010.08.028"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.42.14"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0606039103"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3597"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad984"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3NP00062A"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad344"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1049"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1520\/STP35663S"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.02407"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1128\/mmbr.00019\u201015"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/microbiolres13030031"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad1086"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102105\u201010\u2010421"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioadv\/vbab016"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12859\u2010023\u201005311\u20102"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201043731\u2010z"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564\u2010022\u201001110\u20102"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201004862\u20103"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41396\u2010023\u201001410\u20103"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1101\/2025.05.28.656579"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.02418\u20100"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.040501\u20100"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.2323\/jgam.48.109"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587\u2010019\u20100072\u20108"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010020\u201001056\u20105"},{"key":"e_1_2_8_69_1","unstructured":"PacificBiosciences\/pbipa. PacBio(2025)."},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010023\u201001940\u2010w"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/giaa154"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589\u2010019\u20100400\u20109"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/2041\u2010210X.12613"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1320827"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.006863"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm1000"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btae175"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201007641\u20109"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.059774\u20100"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaf348"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a025808"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msv150"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102105\u201012\u2010124"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbinf.2023.1322477"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst010"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz305"},{"key":"e_1_2_8_87_1","unstructured":"Geneious | Bioinformatics Software for Sequence Data Analysis Geneious https:\/\/www.geneious.com\/."},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4229"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaf1040"},{"key":"e_1_2_8_90_1","volume-title":"Molecular Cloning: A Laboratory Manual","author":"Green M. R.","year":"2012"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102958.1995.tb02262.x"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.76919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/advs.76919","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.76919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T10:19:29Z","timestamp":1787221169000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.76919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":90,"alternative-id":["10.1002\/advs.76919"],"URL":"https:\/\/doi.org\/10.1002\/advs.76919","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,6]]},"assertion":[{"value":"2026-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e76919"}}