{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:29:34Z","timestamp":1786548574476,"version":"build-2736575974"},"reference-count":144,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82571737"],"award-info":[{"award-number":["82571737"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82230046"],"award-info":[{"award-number":["82230046"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH133205"],"award-info":[{"award-number":["MH133205"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH131610"],"award-info":[{"award-number":["MH131610"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Schizophrenia (SCZ) is a neurodevelopmental disorder characterized by heterogeneous symptoms and multifactorial etiologies. Medial ganglionic eminence (MGE) spheroids generated from first\u2010episode schizophrenia (FES) patients revealed accelerated neurodevelopmental trajectories and enhanced hypoxia responses via single\u2010cell transcriptomics. Notably, FES patient\u2010derived MGE spheroids exhibited defective interneuron migration, disrupted synaptic ultrastructure, and diminished network synchronization. To establish causal links, the gestational hypoxia mouse model recapitulated key pathologies, including reduced progenitor proliferation, abbreviated cell cycles, mismatched interneuron subtypes, and schizophrenia\u2010like behavioral deficits in offspring. Critically, maternal administration of N\u2010acetylcysteine (NAC) restored redox homeostasis and rescued both cellular and behavioral phenotypes. Collectively, these results demonstrate that developmental redox disruption directly impairs GABAergic circuit assembly, while supporting targeted antioxidant pharmacotherapy during gestation as a translatable strategy to mitigate neurodevelopmental risk.<\/jats:p>","DOI":"10.1002\/advs.76936","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T14:28:53Z","timestamp":1786544933000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4889-7032","authenticated-orcid":false,"given":"Peiyan","family":"Ni","sequence":"first","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"},{"name":"The MOE Frontier Science Center for Brain Science &amp; Brain\u2010Machine Integration Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiancheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology University of Chinese Academy of Sciences Chinese Academy of Sciences  Beijing China"},{"name":"Institute For Stem Cell and Regeneration Chinese Academy of Sciences  Beijing China"},{"name":"Beijing Institute for Stem Cell and Regenerative Medicine  Beijing China"},{"name":"Key Laboratory of Organ Regeneration and Reconstruction Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youhui","family":"Jiang","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiying","family":"Yao","sequence":"additional","affiliation":[{"name":"College of Life Sciences Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuqing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Tian","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7673-2406","authenticated-orcid":false,"given":"Shiyingnan","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Mental Health Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Ren","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naxin","family":"Xu","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengshan","family":"Fu","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liansheng","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Mental Health Center and Psychiatric Laboratory West China Hospital, Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0860-9289","authenticated-orcid":false,"given":"Xueyu","family":"Qi","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueli","family":"Yu","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0517-3352","authenticated-orcid":false,"given":"Wanjun","family":"Guo","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8737-9978","authenticated-orcid":false,"given":"Sangmi","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Rutgers University  Piscataway NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0165-073X","authenticated-orcid":false,"given":"Fan","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology University of Chinese Academy of Sciences Chinese Academy of Sciences  Beijing China"},{"name":"Institute For Stem Cell and Regeneration Chinese Academy of Sciences  Beijing China"},{"name":"Beijing Institute for Stem Cell and Regenerative Medicine  Beijing China"},{"name":"Key Laboratory of Organ Regeneration and Reconstruction Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3831-901X","authenticated-orcid":false,"given":"Tao","family":"Li","sequence":"additional","affiliation":[{"name":"Affiliated Mental Health Center &amp; Hangzhou Seventh People's Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Clinical and Basic Research on Psychiatric Diseases  Hangzhou Zhejiang China"},{"name":"Zhejiang Engineering Research Center for Intelligent Diagnosis and Treatment of Mental and Psychological Disorders  Hangzhou Zhejiang China"},{"name":"The MOE Frontier Science Center for Brain Science &amp; Brain\u2010Machine Integration Zhejiang University  Hangzhou China"},{"name":"Nanhu Brain\u2010Computer Interface Institute  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0020141"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2019.3360"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2021.21080798"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2022.06.017"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12983"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.06.033"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201086780\u20104"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.09.033"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms12229"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3155"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15872"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010018\u20100313\u2010z"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202300455"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3541"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abk2346"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature22330"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2022.10.006"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3536"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.07.028"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2015.19"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2018.01.007"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2017.02.012"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018\u2010011\u20100807\u20102"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2012.08.002"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1474\u20104422(15)00148\u20109"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/cbmi.4c00074"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1300454110"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2014.104"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2019.08.003"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2018.08.006"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460\u20109568.2000.00229.x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbw038"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2014.01.028"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09\u2010152108"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2020.05.034"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.07.008"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010017\u20100054\u2010x"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010018\u20100140\u20105"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2017.08.017"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.07.017"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2023.08.013"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1915872"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010023\u201006300\u20104"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2013.106"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2013.04.008"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2019.04.002"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41596\u2010018\u20100032\u20107"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2016.11.001"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature25999"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201004640\u20101"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010021\u201000940\u20103"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abj6641"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010017\u20100061\u2010y"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201057053\u2010y"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1704"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.10.009"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896\u20106273(02)00685\u20102"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a005587"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abn6204"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.04.018"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039787"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10229"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418\u2010021\u201000772\u20105"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896\u20106273(03)00818\u20103"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.05.013"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature00779"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759091420981206"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264\u2010021\u201000759\u20109"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010019\u20100423\u20103"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13595"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1159\/000495658"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22179297"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588\u2010022\u201001167\u2010z"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588\u2010018\u20100059\u20102"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2008.02.005"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.04.020"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2387"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.02.030"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004280"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.14\u2010267500"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103205"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.05.026"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0962\u20108924(02)00043\u20100"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.12030305"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.07.023"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2015.15020150"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhq138"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.2890\u201008.2008"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2024.02.010"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004230\u20107"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202216364"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.07.007"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020107277"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep12258"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.126.15.3359"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.08.020"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.3055\u201006.2007"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010023\u201002168\u2010y"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2015.07.005"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2016.01.023"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.20220723"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1211507109"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.22"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2020.620379"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1093\/oons\/kvad004"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.06.013"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2215\u20100366(20)30057\u20102"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010clinpsy\u2010081219\u2010103805"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.12.044"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbad140"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2025.115279"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.10.004"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2013.09.006"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.9.1514"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.5.801"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2013.01.001"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03520100096046"},{"key":"e_1_2_11_119_1","first-page":"84","volume-title":"Structured Clinical Interview for DSM\u2010IV Axis I Disorders SCID\u2010I","author":"First M. B.","year":"1997"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017557"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.713578"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp324"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.107524.110"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq559"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004873"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xpro.2021.100972"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.14806\/ej.17.1.200"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts635"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu638"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw777"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14049"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.05.031"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4091"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2011.0118"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.05.013"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1180"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506580102"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010018\u20100326\u20107"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588\u2010019\u20100397\u20108"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004219"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2859"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4150"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010019\u20101654\u20109"},{"key":"e_1_2_11_145_1","doi-asserted-by":"publisher","DOI":"10.1109\/tbme.2006.873392"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.76936","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/advs.76936","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.76936","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T14:28:55Z","timestamp":1786544935000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.76936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,12]]},"references-count":144,"alternative-id":["10.1002\/advs.76936"],"URL":"https:\/\/doi.org\/10.1002\/advs.76936","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,12]]},"assertion":[{"value":"2025-12-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e76936"}}