{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:19:13Z","timestamp":1787667553884,"version":"build-2736575974"},"reference-count":75,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U25A20661"],"award-info":[{"award-number":["U25A20661"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32301768"],"award-info":[{"award-number":["32301768"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Plant immunity is essential for survival against pathogen invasion. However, enhanced immune activation can restrict arbuscular mycorrhizal (AM) fungal colonization. Therefore, plants must finely balance immunity and symbiosis to optimize fitness, but the key regulators underlying this trade\u2010off remain unclear. Here, we identify a novel mitogen\u2010activated protein kinase, GhNTF3, as a central regulator of the AM symbiosis\u2010immunity balance. Knockdown of\n                    <jats:italic>GhNTF3<\/jats:italic>\n                    promotes AM symbiosis but decreases Verticillium wilt resistance in cotton.\n                    <jats:italic>GhNTF3<\/jats:italic>\n                    overexpression suppresses AM symbiosis. GhNTF3 interacts with GhWAK13, a previously characterized wall\u2010associated kinase that is specifically induced by AM symbiosis, at the plasma membrane. Genetic evidence indicates that\n                    <jats:italic>GhWAK13<\/jats:italic>\n                    functions in association with\n                    <jats:italic>GhNTF3<\/jats:italic>\n                    during AM symbiosis.\n                    <jats:italic>GhWAK13<\/jats:italic>\n                    negatively regulates salicylic acid (SA) accumulation, whereas GhNTF3 positively regulates SA accumulation during AM symbiosis. Knockdown of SA biosynthesis genes or the SA receptor gene\n                    <jats:italic>GhNPR1<\/jats:italic>\n                    significantly enhanced AM fungal colonization, whereas exogenous SA application strongly inhibited symbiosis. Moreover, GhNTF3 interacts with GhJAZ6 in the nucleus to enhance Verticillium wilt resistance, potentially through SA accumulation in cotton. Collectively, our findings identify a molecular module in which the interplay between GhNTF3 and GhWAK13 dynamically balances AM symbiosis and Verticillium wilt resistance through antagonistic regulation of the SA signaling pathway.\n                  <\/jats:p>","DOI":"10.1002\/advs.77315","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:25:52Z","timestamp":1787664352000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Mitogen\u2010Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis\u2010Immunity Trade\u2010Off in Cotton by Regulating Salicylic Acid Biosynthesis"],"prefix":"10.1002","author":[{"given":"Shuangjie","family":"Jia","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cotton Bio\u2010Breeding and Integrated Utilization School of Life Sciences Henan University  Kaifeng China"},{"name":"Institute of Edible Fungi Henan Academy of Agricultural Sciences  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingshang","family":"Wen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cotton Bio\u2010Breeding and Integrated Utilization School of Life Sciences Henan University  Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihang","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cotton Bio\u2010Breeding and Integrated Utilization School of Life Sciences Henan University  Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2587-709X","authenticated-orcid":false,"given":"Meina","family":"Feng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cotton Bio\u2010Breeding and Integrated Utilization School of Life Sciences Henan University  Kaifeng 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of Life Sciences Henan University  Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5916-7564","authenticated-orcid":false,"given":"Xiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cotton Bio\u2010Breeding and Integrated Utilization School of Life Sciences Henan University  Kaifeng China"},{"name":"College of Life Sciences Henan Agricultural University  Zhengzhou Henan 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