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Integration with anti\u2010PD\u20101 therapy further reinvigorates cytotoxic T lymphocytes and establishes antitumor immune memory to suppress tumor progression and metastasis, offering a multimodal therapeutic strategy for large HCC.\n                  <\/jats:p>","DOI":"10.1002\/advs.77933","type":"journal-article","created":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T18:00:31Z","timestamp":1790532031000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Glutaminolysis Blockade\u2010Empowered Bimodal Nanodepot for Spatially Complementary Sono\u2010Thermal Ablation via PANoptosis and STING Activation Against Large Tumors"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5898-9913","authenticated-orcid":false,"given":"Yi\u2010Ming","family":"Liu","sequence":"first","affiliation":[{"name":"Center of Interventional Radiology and Vascular Surgery Department of Radiology Zhongda Hospital 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