{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:09:19Z","timestamp":1790784559457,"version":"4.1.0"},"reference-count":68,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFD1201802"],"award-info":[{"award-number":["2022YFD1201802"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Plant viruses have evolved sophisticated virulence strategies to counteract host antiviral defenses. Blue light, as an important environmental signal, can regulate plant growth and tolerance to biological stress. Nevertheless, how blue light regulates plant responses to antiviral immunity remains largely obscure. Here, we demonstrate that blue light suppresses rice black\u2010streaked dwarf virus (RBSDV) replication. The blue light receptor ZmPHR2 functions as a key immune component, positively regulating maize resistance to RBSDV. Mechanistically, ZmPHR2 interacts with ZmISP in chloroplasts to trigger a defensive reactive oxygen species (ROS) burst, thereby conferring resistance. The RBSDV effector P6 enhances the ZmPHR2\u2010ZmISP interaction, alters their subcellular distribution, and suppresses ROS accumulation. A functionally analogous P6\u2010OsPHR2\u2010OsISP module similarly mediates RBSDV resistance in rice. Our findings reveal that blue light perception directly activates antiviral defense pathways, uncovering a molecular basis for RBSDV resistance. This study provides a theoretical basis for artificially modifying the blue light receptor protein to enhance the resistance of cereal crops.<\/jats:p>","DOI":"10.1002\/advs.78050","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:41:38Z","timestamp":1790782898000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Blue Light Receptor PHR2\u2010Mediated Spectrum Antiviral Immunity"],"prefix":"10.1002","author":[{"given":"Runyi","family":"Chen","sequence":"first","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"},{"name":"National Key Laboratory of Smart Farm Technology and System College of Agriculture Northeast Agricultural University  Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4932-3938","authenticated-orcid":false,"given":"Yuxin","family":"Tai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhua","family":"Mu","sequence":"additional","affiliation":[{"name":"Shandong Academy of Agricultural Sciences  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Liu","sequence":"additional","affiliation":[{"name":"Shandong Academy of Agricultural Sciences  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gongjian","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Lu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo","family":"Shi","sequence":"additional","affiliation":[{"name":"Hinggan League Academy of Agricultural and Animal Husbandry Sciences Hinggan League China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqiang","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jienan","family":"Han","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuanfang","family":"Hao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"},{"name":"National Nanfan Research Institute (Sanya) Chinese Academy of Agricultural Sciences  Sanya China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingshun","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Degui","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjun","family":"Yong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhennan","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"},{"name":"National Nanfan Research Institute (Sanya) Chinese Academy of Agricultural Sciences  Sanya China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4798-6351","authenticated-orcid":false,"given":"Jianfeng","family":"Weng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"},{"name":"National Nanfan Research Institute (Sanya) Chinese Academy of Agricultural Sciences  Sanya China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhai","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop Sciences Chinese Academy of Agricultural Sciences  Beijing China"},{"name":"National Nanfan Research Institute (Sanya) Chinese Academy of Agricultural Sciences  Sanya China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2025.08.007"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2024.07.008"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201054470\u20100"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201036382\u20107"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsptsci.3c00355"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiae110"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2020.11.016"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08719"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477\u2010023\u201001461\u20106"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/366162a0"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koab124"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.160895"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.70058"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2024.12.003"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201045086\u20105"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.20.00243"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.10.031"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiaf538"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.113.121830"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.108.132217"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.15046"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.17929"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201041503\u20103"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.13967"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.230334397"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201024617\u20104"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010022\u201009001\u2010w"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/aab.12184"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2017.02.004"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep29848"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007050170006"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1918254117"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2016673118"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.13966"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201014372\u20103"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201051726\u20107"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-023-01514-w"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf6005"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2023.100644"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koaf196"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koae311"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05286"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.13820"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiab434"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/ssp106"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2012.00222"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.arplant.49.1.249"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.167569"},{"issue":"7","key":"e_1_2_9_50_1","first-page":"1364","article-title":"ROS Generation in Peroxisomes and Its Role in Cell Signaling","volume":"57","author":"R\u00edo L. A.","year":"2016","journal-title":"Plant and Cell Physiology"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12386"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2017.08.002"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens11091039"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS\u201003\u201020\u20100495\u2010RE"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12284\u2010019\u20100310\u20101"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.17961"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00122\u2010022\u201004214\u20109"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23010287"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcp\/pcs097"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0176\u20101617(11)80347\u20100"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010019\u201013487\u20106"},{"key":"e_1_2_9_62_1","volume-title":"Genetic Variation and Pathogenic Pathway Analysis of Rice Black\u2010Streaked Dwarf Virus Infecting Maize","author":"Zhou Y.","year":"2015"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2017.11.013"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.18.00034"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep23890"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.73"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msw054"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab447"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.199"}],"container-title":["Advanced Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.78050","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/advs.78050","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/advs.78050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:41:40Z","timestamp":1790782900000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/advs.78050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":68,"alternative-id":["10.1002\/advs.78050"],"URL":"https:\/\/doi.org\/10.1002\/advs.78050","archive":["Portico"],"relation":{},"ISSN":["2198-3844","2198-3844"],"issn-type":[{"value":"2198-3844","type":"print"},{"value":"2198-3844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"assertion":[{"value":"2026-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e78050"}}