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Although antibiotics effectively combat bacteria, the emergence of antibiotic resistance severely compromises their efficacy. Therefore, an efficient and practical approach is urgently sought to improve antibacterial efficiency. Porphyrins, as typical photosensitizers (PSs), serve as favorable candidates for constructing porous materials with enhanced properties due to their advantages, including easy modification, strong light\u2010absorbing ability, and good biocompatibility. Typically, porphyrin\u2010based porous materials are categorized into four classic types according to their linkage modes, including porphyrin\u2010based metal\u2013organic frameworks (PMOFs), porphyrin\u2010based covalent organic frameworks (PCOFs), porphyrin\u2010based hydrogen\u2010bonded organic frameworks (PHOFs), and amorphous porphyrin\u2010based porous polymers (APPPs). This review summarizes antimicrobial advances in porphyrin\u2010based porous materials from the perspective of synthetic strategies and structural design in the past 10 years. Key areas include healthcare, food, agriculture, functional textiles, and wastewater treatment. Moreover, the challenges and future development directions in this field are discussed. This review inspires and motivates more researchers to focus on the innovative construction of porphyrin\u2010based porous materials to facilitate the efficient realization of antimicrobial applications.<\/jats:p>","DOI":"10.1002\/advs.78159","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:48:45Z","timestamp":1791352125000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Porphyrin\u2010Based Porous Materials for Antibacterial Applications"],"prefix":"10.1002","author":[{"given":"Xiao\u2010Xue","family":"Liang","sequence":"first","affiliation":[{"name":"China\u2010Japan Union Hospital of Jilin University and College of Chemistry Jilin University  Changchun People\u2019 Republic of China"},{"name":"College of Chemistry Liaoning University  Shenyang People\u2019 Republic of 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