{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:48:22Z","timestamp":1791866902315,"version":"4.3.4"},"reference-count":53,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22274095"],"award-info":[{"award-number":["22274095"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["GK202302004"],"award-info":[{"award-number":["GK202302004"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Science"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Photodynamic therapy (PDT) for deep\u2010seated tumors is fundamentally constrained by limited tissue penetration, the ultrashort lifetime of singlet oxygen (\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    ), and the lack of reusable oxygen delivery systems. Herein, we report a near\u2010infrared (NIR) triggered rechargeable \u201csinglet oxygen battery\u201d that enables sustained and cyclic\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    supply for enhanced phototherapy. A series of aza\u2010boron\u2010dipyrromethene (aza\u2010BODIPY) probes (NBDP, ABDP, and PBDP) are rationally engineered by integrating distinct\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    carriers, among which PBDP exhibits optimal performance. Upon 808\u00a0nm irradiation (5\u00a0min), PBDP nanoparticles (NPs), as the singlet oxygen battery, generate abundant\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    that is reversibly captured via [4+2] cycloaddition with 2\u2010pyridone to form endoperoxides (EPOs), while simultaneously enabling efficient photothermal conversion. After light cessation, stored\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    is thermally released from EPOs for up to 1\u00a0h, realizing sustained therapeutic action. Notably, the system supports multiple charging\u2013discharging cycles with negligible performance decay. In vivo NIR\u2010II imaging reveals efficient tumor accumulation, leading to significant tumor suppression via synergistic sustained PDT\/PTT (photothermal therapy) with excellent biocompatibility. This work provides a rechargeable\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    storage and release platform by integrating NIR activation, self\u2010heating\u2010assisted discharge, and cyclic phototherapeutic capability, offering a promising strategy to improve the efficiency and durability of phototherapy for tumor treatment.\n                  <\/jats:p>","DOI":"10.1002\/advs.78284","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:27:06Z","timestamp":1791865626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Near\u2010Infrared Triggered Rechargeable Singlet Oxygen Battery for Sustained Phototherapy: Fast Charging and Long\u2010Lasting Discharging"],"prefix":"10.1002","author":[{"given":"Yuxin","family":"Ren","sequence":"first","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry Key Laboratory of Analytical Chemistry For Life Science of Shaanxi Province Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an Shaanxi Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry Key Laboratory of Analytical Chemistry For Life Science of Shaanxi Province Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an Shaanxi Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry Key Laboratory of Analytical Chemistry For Life Science of Shaanxi Province Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an Shaanxi Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiqi","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry Key Laboratory of Analytical Chemistry For Life Science of Shaanxi Province Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an Shaanxi Province People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqing","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry Key Laboratory of Analytical Chemistry For Life Science of Shaanxi Province Ministry of Education School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an Shaanxi Province People's Republic of 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