{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:23:35Z","timestamp":1784118215734,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,7,30]],"date-time":"2023-07-30T00:00:00Z","timestamp":1690675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K08NS089976"],"award-info":[{"award-number":["K08NS089976"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS126761"],"award-info":[{"award-number":["R01NS126761"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Elect Materials"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Effective stroke recovery therapeutics remain limited. Stem cell therapies have yielded promising results, but the harsh ischemic environment of the post\u2010stroke brain reduces their therapeutic potential. Previously, a conductive polymer system that enables stem cell delivery with simultaneous electrical modulation of the cells and surrounding neural environment is\u00a0developed. This wired conductive polymer system proved\u00a0efficacious in optimizing ideal conditions for stem cell mediated motor improvements in a rodent model of stroke. To further enable preclinical studies and enhance translational potential, a method to improve this system by eliminating its dependence upon a tethered power source is identified. A wirelessly powered, electrically conductive polymer system that eases therapeutic application and enables full mobility is herein developed. As a proof of concept, it is demonstrated that the wirelessly powered system is able to stimulate neural stem cells in vitro, as well as in vivo in a rodent model of stroke. This system modulates the stroke microenvironment and increases the production of endogenous stem cells. In summation, this novel, wirelessly powered conductive polymer system can serve as a mobile platform for a wide variety of therapeutics involving electrical stimulation.<\/jats:p>","DOI":"10.1002\/aelm.202300369","type":"journal-article","created":{"date-parts":[[2023,7,30]],"date-time":"2023-07-30T22:15:54Z","timestamp":1690755354000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Wirelessly Powered\u2010Electrically Conductive Polymer System for Stem Cell Enhanced Stroke Recovery"],"prefix":"10.1002","volume":"9","author":[{"given":"Sruthi","family":"Santhanam","sequence":"first","affiliation":[{"name":"Department of Neurology and Neurological Sciences Stanford University School of Medicine 300 Pasteur Dr., MC5778 Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering Stanford University 350 Jane Stanford Way Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byeongtaek","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Sciences Stanford University School of Medicine 300 Pasteur Dr., MC5778 Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly W.","family":"McConnell","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Sciences Stanford University School of Medicine 300 Pasteur Dr., MC5778 Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8253-7113","authenticated-orcid":false,"given":"Matine M.","family":"Azadian","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Sciences Stanford University School of Medicine 300 Pasteur Dr., MC5778 Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jainith J.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Sciences Stanford University School of Medicine 300 Pasteur Dr., MC5778 Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily E.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Sciences Stanford University School of Medicine 300 Pasteur Dr., MC5778 Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Tanabe","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering Stanford University 350 Jane Stanford Way Stanford CA 94305 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada S. 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