{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:03:10Z","timestamp":1790690590834,"version":"4.1.0"},"reference-count":65,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Genetics"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The absence of horns (polled trait) in cattle is associated with better animal welfare by reducing the need for dehorning. In Brahman cattle, population size and the scarcity of phenotypic records challenge the accuracy of genomic predictions for this trait. This study aimed to evaluate the genetic architecture of this trait in Brahman cattle using single\u2010breed and multi\u2010breed genomic prediction models, including metafounders, and to assess the influence of phenotypic classifications on heritability, prediction accuracy, bias, and dispersion. Phenotypic and genotypic data from 14\u2009333 Nelore and Brahman animals were analyzed using threshold and linear models implemented in the BLUPF90+ software suite. Single\u2010breed models (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200912) were considered phenotypes (polled, scab, scur, horned), while multi\u2010breed models (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910) incorporated metafounders and breed effects. Variance components were estimated via threshold models with Gibbs sampling, and predictive ability was assessed using the LR method with datasets. Single\u2010breed models showed heritability estimates (\n                    <jats:italic>h<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    ) ranging from 0.56 to 0.72, but with predictive ability reflecting the Brahman population size. Multi\u2010breed models improved predictive performance. Results were obtained with Model 20, which included alternative phenotypes, metafounders, and breed effects, yielding accuracy (0.79), reduced bias (0.36), and dispersion close to 1. These findings demonstrate that the polled trait in Brahman cattle exhibits additive genetic variability amenable to selection. The use of multi\u2010breed analyses and metafounders enhances predictive accuracy, providing a strategy for populations and traits, and enables the inclusion of traits as genomic selection criterion to increase allele frequency in Brahman cattle and improve animal welfare.\n                  <\/jats:p>","DOI":"10.1002\/age.70211","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:14:20Z","timestamp":1790687660000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Implementation of Metafounders in the Genomic Prediction for the Polled Trait in Brahman Cattle Using a Multi\u2010Breed Population"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5402-9551","authenticated-orcid":false,"given":"Lanna Maryana Costa","family":"Pereira","sequence":"first","affiliation":[{"name":"Federal University of Goi\u00e1s  Goi\u00e2nia Goi\u00e1s Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4094-2011","authenticated-orcid":false,"given":"Fernando","family":"Baldi","sequence":"additional","affiliation":[{"name":"School of Animal Science and Food Engineering University of S\u00e3o Paulo  Pirassununga S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9012-520X","authenticated-orcid":false,"given":"Ludmilla Costa","family":"Brunes","sequence":"additional","affiliation":[{"name":"Federal University of Goi\u00e1s  Goi\u00e2nia Goi\u00e1s Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6426-8057","authenticated-orcid":false,"given":"Lu\u00eds","family":"Camaripano","sequence":"additional","affiliation":[{"name":"Grupo Ganadero Estancias Esp\u00edritu  Santa Cruz de la Sierra Bolivia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7274-0134","authenticated-orcid":false,"given":"Cl\u00e1udio Ulh\u00f4a","family":"Magnabosco","sequence":"additional","affiliation":[{"name":"Embrapa Cerrados  Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2009\u20102730"},{"key":"e_1_2_11_3_1","unstructured":"ANCP.2024.\u201cSum\u00e1rio de Touros das Ra\u00e7as Nelore Guzer\u00e1 Brahman e Tabapu\u00e3: Edi\u00e7\u00e3o Agosto de 2024.\u201dAssocia\u00e7\u00e3o Nacional de Criadores e Pesquisadores (ANCP)."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102052.2003.01079.x"},{"key":"e_1_2_11_5_1","first-page":"125","article-title":"The Facts of Heredity in the Light of Mendel's Discovery","volume":"1","author":"Bateson W.","year":"1902","journal-title":"Reports to the Evolution Committee of the Royal Society"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2017\u201013366"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1071\/AN17436"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022242"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/1828051X.2022.2050471"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2021\u201021505"},{"issue":"434","key":"e_1_2_11_11_1","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1080\/01621459.1996.10476956","article-title":"Markov Chain Monte Carlo Convergence Diagnostics: A Compa\u2010 Rative Review","volume":"91","author":"Cowles M. 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