{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:58:19Z","timestamp":1772117899798,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T00:00:00Z","timestamp":1600300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aging Medicine"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Atypical presentations of COVID\u201019 pose difficulties for early isolation and treatment, particularly in institutional care settings. We aimed to characterize the presenting symptoms and associated mortality of COVID\u201019 in older adults, focusing on care home residents admitted to secondary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study of 134 consecutive inpatients over 80\u00a0years old hospitalized with PCR confirmed COVID\u201019 in the United Kingdom. Symptoms at presentation and frailty were analysed. Differences between community dwelling and care home residents, and associations with mortality, were assessed using between\u2010group comparisons and logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Care home residents were less likely to experience cough (46.9% vs 72.9%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.002) but more likely to present with delirium (51.6% vs 31.4%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.018), particularly hypoactive delirium (40.6% vs 24.3%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.043). Mortality was more likely with increasing frailty (OR 1.25, 95% CI 1.00, 1.58,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.049) and those presenting with anorexia (OR 3.20, 95% CI 1.21, 10.09,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.028). There were no differences in mortality or length of stay based on residential status.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>COVID\u201019 in older adults often presents with atypical symptoms, particularly in those admitted from institutional care. These individuals have a reduced incidence of cough and increased hypoactive delirium. Individuals presenting atypically, especially with anorexia, have higher mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/agm2.12126","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T06:02:51Z","timestamp":1600322571000},"page":"237-244","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Atypical presentations of COVID\u201019 in care home residents presenting to secondary care: A UK single centre study"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2831-6993","authenticated-orcid":false,"given":"Mark James","family":"Rawle","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine Barnet Hospital Royal Free London NHS Foundation Trust London UK"},{"name":"MRC Unit for Lifelong Health and Ageing at UCL London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah Lee","family":"Bertfield","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine Barnet Hospital Royal Free London NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon Edward","family":"Brill","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Barnet Hospital Royal Free London NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_2_9_3_1","unstructured":"UK Government.Coronavirus (COVID\u201019) in the UK;2020.https:\/\/coronavirus.data.gov.uk\/?_ga=2.137891512.944000509.1587819030\u20101391566006.1580594784. 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