{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:04:24Z","timestamp":1789725864848,"version":"4.0.1"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003509","name":"\u00d6rebro Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003509","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014195","name":"Region V\u00e4rmland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014195","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aging Medicine"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Older persons are often referred to emergency departments due to acute functional decline, that is, reduced activities of daily living occurring in the days before hospitalization, frequently driven by acute medical conditions. We aimed to describe frailty in the oldest hospitalized patients presenting with acute functional decline and evaluate predictors of death, severe frailty and nursing home admission after 3\u20136\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included 119 persons with acute functional decline, aged \u2265\u200980\u2009years, \u2265\u20095 systemic diagnoses, \u2265\u20095 drugs daily, from an acute geriatric ward and reassessed after 3\u20136\u2009months. All were evaluated with comprehensive geriatric assessment. Severe frailty was defined as Clinical Frailty Scale 7\u20138.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010one (34.4%) were free from severe frailty at baseline and 32 (48.5%) at follow\u2010up. Male sex (adjusted OR 11.820, 95% confidence interval [CI] 3.670\u201338.120), Clinical Dementia Rating (CDR) \u2265\u20090.5 (adjusted OR 3.920, 95% CI 1.020\u201315.100), severe frailty at baseline (adjusted OR 6.930, 95% CI 1.830\u201326.210), type 2 diabetes (adjusted OR 7.460, 95% CI 2.040\u201327.250), and cancer (adjusted OR 5.640, 95% CI 1.040\u201330.690) were associated with death at follow\u2010up. Hearing impairment (adjusted OR 7.060, 95% CI 1.430\u201334.760), CDR\u2009\u2265\u20090.5 (adjusted OR 5.390, 95% CI 1.260\u201323.070), and nursing home living before admission (adjusted OR 4.260, 95% CI 1.010\u201317.920) were associated with severe frailty at follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Many persons with acute functional decline have severe frailty. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living seem to increase the risk of severe frailty or death and should be considered when person\u2010centered care is planned for hospitalized older people.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/agm2.70104","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T08:31:09Z","timestamp":1787214669000},"page":"374-383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7642-4630","authenticated-orcid":false,"given":"Ali","family":"Vahedi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Section of Geriatric Medicine Central Hospital Karlstad  Region V\u00e4rmland Sweden"},{"name":"School of Medical Sciences \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Eriksdotter","sequence":"additional","affiliation":[{"name":"Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society Karolinska Institutet  Huddinge Sweden"},{"name":"Theme Inflammation and Aging Karolinska University Hospital  Huddinge Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hege","family":"Ihle\u2010Hansen","sequence":"additional","affiliation":[{"name":"Department of Acute Medicine Oslo University Hospital  Oslo Norway"},{"name":"Institute of Health and Society University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torgeir Bruun","family":"Wyller","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"},{"name":"Department of Geriatric Medicine Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Rita","family":"\u00d8kseng\u00e5rd","sequence":"additional","affiliation":[{"name":"The Norwegian Health Association  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brynjar","family":"Fure","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Geriatric Medicine Central Hospital Karlstad  Region V\u00e4rmland Sweden"},{"name":"School of Medical Sciences \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010023\u201004192\u20107"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gerinurse.2016.01.001"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12160"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afac007"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2301292"},{"issue":"11","key":"e_1_2_14_7_1","first-page":"S10","article-title":"Incidence of Dementia and Major Subtypes in Europe: A Collaborative Study of Population\u2010Based Cohorts. 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