{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:21:31Z","timestamp":1759335691775,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T00:00:00Z","timestamp":1532649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004820","name":"Mochida Pharmaceutical Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004820","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Few studies have investigated surgical outcomes following a colectomy in pediatric patients with ulcerative colitis (UC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study aimed to determine long\u2010term outcomes in a large cohort of pediatric patients who underwent proctocolectomy with ileal pouch\u2010anal anastomosis (IPAA) for UC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pediatric patients (&lt;17\u00a0years old) who underwent surgery at 12 different hospitals in Japan between May 1979 and March 2015 were included in this study. Information was obtained by the use of a questionnaire survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 113 (53.3%) male and 99 (46.7%) female pediatric patients. The most common indication for elective surgery was failure of medical management, whereas emergency surgery was carried out for fulminant cases. A hand\u2010sewn IPAA was used with a mucosectomy in 112 (52.8%), stapled anastomosis in 93 (43.9%), and not specified in 7 (3.3%) patients. Small bowel obstruction and surgical site infection were the most frequent early postoperative complications (POC), whereas pouchitis, small bowel obstruction, and perianal fistula were frequent late POC. The most common late POC was pouchitis, found in 38 (17.9%) of the patients, whereas pouch failure was noted in 11 patients at the latest follow\u2010up examination. Cumulative pouch survival rate after 10\u00a0years was 91.7%. There were no significant differences regarding gender or anastomotic procedure in relation to cumulative pouch survival rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>To avoid pouch failure following an IPAA procedure, it is important to recognize that pouchitis or an anal fistula may lead to this condition in pediatric UC patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ags3.12198","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T14:38:12Z","timestamp":1532702292000},"page":"428-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Long\u2010term outcomes following restorative proctocolectomy ileal pouch\u2010anal anastomosis in pediatric ulcerative colitis patients: Multicenter national study in Japan"],"prefix":"10.1002","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9144-5782","authenticated-orcid":false,"given":"Hiroki","family":"Ikeuchi","sequence":"first","affiliation":[{"name":"Department of Inflammatory Bowel Disease Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoi","family":"Uchino","sequence":"additional","affiliation":[{"name":"Department of Inflammatory Bowel Disease Surgery Hyogo College of Medicine Nishinomiya Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Sugita","sequence":"additional","affiliation":[{"name":"Department of Inflammatory Bowel Disease Yokohama Municipal Citizen's Hospital Yokohama Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kitaro","family":"Futami","sequence":"additional","affiliation":[{"name":"Department of Surgery Fukuoka University Chikushi Hospital Chikushino, Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouhei","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Surgical and Molecular Pathophysiology Tohoku University Graduate School of Medicine Sendai Miyagi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology The University of Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutaka","family":"Koganei","sequence":"additional","affiliation":[{"name":"Department of Inflammatory Bowel Disease Yokohama Municipal Citizen's Hospital Yokohama Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Kusunoki","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and Pediatric Surgery Mie University Graduate School of Medicine Tsu Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and Pediatric Surgery Mie University Graduate School of Medicine Tsu Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riichiro","family":"Nezu","sequence":"additional","affiliation":[{"name":"Department of Surgery Nishinomiya Municipal Center Hospital Nishinomiya Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Kimura","sequence":"additional","affiliation":[{"name":"Inflammatory Bowel Disease Center Yokohama City University Medical Center Yokohama Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Coloproctology Center Tohoku Rosai Hospital Sendai Miyagi 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