{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:34:44Z","timestamp":1792017284819,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T00:00:00Z","timestamp":1563753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Japan Surgical Society"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the frequency and risk factors of perioperative, symptomatic venous thromboembolism (<jats:styled-content style=\"fixed-case\">VTE<\/jats:styled-content>) after gastroenterological surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We assessed the frequency of and risk factors for <jats:styled-content style=\"fixed-case\">VTE<\/jats:styled-content> after eight gastroenterological procedures (total 516\u00a0217 cases including, gastrectomy, total gastrectomy, hepatectomy, esophagectomy, right hemicolectomy, low anterior resection, pancreaticoduodenectomy, and acute pan\u2010peritonitis surgery) based on data from the National Clinical Database. Data collected between 2011 and 2013 (382\u00a0124 cases) were used as a test set, and data from 2014 (134\u00a0093 cases) were used as a validation set.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The frequency of deep vein thrombosis (<jats:styled-content style=\"fixed-case\">DVT<\/jats:styled-content>) was 0.3% (382\u00a0124 cases), and the incidence of pulmonary embolism (<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>) was 0.2% (382\u00a0124 cases) ranging from 0.1% to 0.7% for <jats:styled-content style=\"fixed-case\">DVT<\/jats:styled-content> and from 0.1% and 0.3% for <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> among eight surgeries, respectively. Analyses using pre\u2010and intra\u2010operative factors identified the top three risk factors for <jats:styled-content style=\"fixed-case\">VTE<\/jats:styled-content> as esophagectomy, pancreaticoduodenectomy, and hepatectomy. Using pre\u2010, intra\u2010, and postoperative factors, the second through fourth risk factors were sepsis, prolonged ventilation &gt;48\u00a0hours and readmission within 30\u00a0days. The highest risks factor for <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> using pre\u2010, intra\u2010, and postoperative factors were any cardiac events. Unplanned intubation was the fourth risk factor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The risk for <jats:styled-content style=\"fixed-case\">DVT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> differed for each surgical procedure. <jats:styled-content style=\"fixed-case\">VTE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> risk factors changed after considering postoperative factors. It may be necessary to reconsider the prophylaxis depending on whether the complication occurs after surgery, particularly breathing and cardiac complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ags3.12275","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T11:44:28Z","timestamp":1563795868000},"page":"534-543","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Frequency and risk factors for venous thromboembolism after gastroenterological surgery based on the Japanese National Clinical Database (516\u00a0217 cases)"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1680-724X","authenticated-orcid":false,"given":"Taishi","family":"Hata","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine Osaka University Suita Osaka 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