{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:18:39Z","timestamp":1789600719942,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Despite being reported safety, the advantages of transanal minimally invasive proctocolectomy (TAMIP) are controversial, and comparative studies on postoperative defecation function between ileal pouch\u2010anal anastomosis (IPAA) using laparoscopic transanal manipulation (TAMIP\u2010IPAA) and without this technique (traditional IPAA) are lacking. This study analyzed TAMIP's impact on short\u2010term and postoperative defecation function in patients with ulcerative colitis (UC) to evaluate its safety and feasibility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Inclusion criteria comprised patients with UC undergoing minimally invasive proctocolectomy at our hospital from May 2014 to May 2023. The TAMIP\u2010IPAA approach involved precise rectal mucosa removal while preserving the sphincter muscle during laparoscopic transanal manipulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the evaluation of short\u2010term outcomes for 71 patients undergoing proctocolectomy, the TAMIP group (37 patients) outperformed the non\u2010TAMIP group in operative time (395 vs. 289\u2009min, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and postoperative hospital stay (12 vs. 8\u2009days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Additionally, TAMIP\u2010IPAA demonstrated advantages over traditional IPAA (seven patients), in operative time (443 vs. 289\u2009min, <jats:italic>p<\/jats:italic>\u2009=\u20090.006), intraoperative blood loss (392 vs. 130\u2009mL, <jats:italic>p<\/jats:italic>\u2009=\u20090.001), postoperative hospital stay (18 vs. 8\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.003), anastomotic leakage (42.9% vs. 8.1%, <jats:italic>p<\/jats:italic>\u2009=\u20090.041), and re\u2010admission within 30\u2009days (57.1% vs. 8.1%, <jats:italic>p<\/jats:italic>\u2009=\u20090.009). Wexner scores were significantly superior in the TAMIP\u2010IPAA group at 6\u2009months (14.5 vs. 8.0 points, <jats:italic>p<\/jats:italic>\u2009=\u20090.029) and 1\u2009year post stoma closure (14.0 vs. 7.0 points, <jats:italic>p<\/jats:italic>\u2009=\u20090.020), indicating enhanced short\u2010term outcomes and defecation function compared to traditional IPAA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TAMIP\u2010IPAA for UC has the potential to offer promising benefits, including the enhancement of short\u2010term outcomes and the improvement of defecation function.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ags3.12844","type":"journal-article","created":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T14:38:47Z","timestamp":1720967927000},"page":"1056-1066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transanal minimally invasive proctectomy for ulcerative colitis is beneficial in terms of short\u2010term outcomes and defecation function"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3380-7233","authenticated-orcid":false,"given":"Marie","family":"Hanaoka","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery Tokyo Medical and Dental University  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7885-2276","authenticated-orcid":false,"given":"Yusuke","family":"Kinugasa","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Tokyo Medical and Dental University  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Tokyo Medical and Dental University  Bunkyo\u2010ku Tokyo 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