{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:09:03Z","timestamp":1793142543302,"version":"4.5.0"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The clinical characteristics of colonic diverticular perforation are poorly understood. We aimed to clarify the clinical characteristics of colonic diverticular perforation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent surgery for colonic diverticular perforation from 2011 to 2021 were retrospectively evaluated. The patients were divided into right\u2010 and left\u2010sided colon cohorts according to their perforation location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 1129 patients with gastrointestinal perforation, 138 had colonic diverticular perforation. The sigmoid colon was the most common perforation site. The patients were categorized into right\u2010sided (20 patients) and left\u2010sided (118 patients) colon cohorts. The number of patients with colonic diverticular perforation increased with age, as did the proportion of left\u2010sided perforations. The left\u2010sided cohort had significantly higher mean age, hemoglobin, and serum albumin levels than the right\u2010sided cohort. The blood urea nitrogen and serum creatinine levels were significantly lower in the right\u2010sided cohort. The proportion of patients with colostomy, the proportion of patients with postoperative complications, and the length of intensive care unit stay during hospitalization were significantly longer in the left\u2010sided cohort. The left\u2010sided cohort also had a considerably longer mean hospital stay and higher mean hospitalization costs than the right\u2010sided colon cohort. An age of \u2265\u200975\u2009years tended to be associated with a prolonged hospital stay and high hospitalization costs in the left\u2010sided colon cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The patients' conditions, length of hospital stay, and hospitalization costs were significantly worse in the left\u2010 than right\u2010sided colon cohort. The clinical characteristics differed according to the location of the diverticular perforation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ags3.70033","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T12:40:11Z","timestamp":1747140011000},"page":"1036-1046","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical and Economic Insights Into Surgery for Colonic Diverticular Perforation: A Long\u2010Term Observational Cohort Study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3211-995X","authenticated-orcid":false,"given":"Minoru","family":"Fujita","sequence":"first","affiliation":[{"name":"Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine Kawasaki Medical School General Medical Center  Okayama Japan"},{"name":"Division of Gastroenterology, Department of Gastroenterology and Hepatology Kawasaki 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