{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:31:57Z","timestamp":1790962317671,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K15447"],"award-info":[{"award-number":["23K15447"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Pancreatoduodenectomy (PD) is a highly invasive surgical procedure associated with postoperative malnutrition. Laparoscopic pancreatoduodenectomy (LPD) is a minimally invasive alternative, but its long\u2010term effects on nutritional outcomes remain unclear. This study aimed to compare long\u2010term nutritional outcomes between LPD and open PD (OPD) and to identify factors influencing postoperative nutritional status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on 65 patients who underwent PD. Nutritional indicators, including the psoas muscle index (PMI), prognostic nutritional index, and liver\u2010to\u2010spleen ratio, were assessed at 3, 6, and 12\u2009months postoperatively. Multivariate analysis was performed to determine factors affecting nutritional outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The LPD group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200936) demonstrated better PMI preservation at 12\u2009months compared with the OPD group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200929) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), with significantly lower fatty liver incidence (3.7% vs. 22.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.038) and higher prognostic nutritional index values at 3\u2009months (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.029). LPD was identified as an independent factor for improved PMI (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020). Additionally, LPD was associated with reduced blood loss and shorter hospital stays.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LPD improves long\u2010term nutritional outcomes by preserving muscle mass and reducing metabolic disruptions, thus supporting its role in enhancing postoperative recovery and quality of life. Further prospective studies are warranted to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ags3.70038","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T23:39:00Z","timestamp":1748302740000},"page":"1263-1272","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Long\u2010Term Nutritional Benefits of Laparoscopic Pancreatoduodenectomy Over Open Surgery"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0535-103X","authenticated-orcid":false,"given":"Koki","family":"Kurahashi","sequence":"first","affiliation":[{"name":"Division of Hepato\u2010Biliary\u2010Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine Kyoto University  Kyoto 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Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Ishida","sequence":"additional","affiliation":[{"name":"Division of Hepato\u2010Biliary\u2010Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9577-330X","authenticated-orcid":false,"given":"Satoshi","family":"Ogiso","sequence":"additional","affiliation":[{"name":"Division of Hepato\u2010Biliary\u2010Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2266-7722","authenticated-orcid":false,"given":"Yoichiro","family":"Uchida","sequence":"additional","affiliation":[{"name":"Division of Hepato\u2010Biliary\u2010Pancreatic 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