{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:08:52Z","timestamp":1784297332585,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H26\u2010J045"],"award-info":[{"award-number":["H26\u2010J045"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP16ck0106048"],"award-info":[{"award-number":["JP16ck0106048"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Higher volumes of surgical procedures have been associated with better patient outcomes. However, few large\u2010scale studies have evaluated interinstitutional variation to verify the generalization and standardization of gastric cancer surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A randomized phase III trial (JCOG1001) was conducted to compare standard and experimental surgeries for advanced gastric cancer. Of the 1204 patients with cT3\u20134b gastric adenocarcinoma enrolled in JCOG1001 between 2010 and 2015, this study only included hospitals that enrolled at least three patients and patients in the standard surgery arm in this analysis. Mixed\u2010effects models were used to examine the short\u2010 and long\u2010term outcome data for 595 patients from 47 institutes after adjusting for clinical backgrounds. Spearman's correlation coefficients were calculated for associations between the estimated outcomes and hospital or surgeon volumes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A degree of variation in the 5\u2010year overall survival (OS) for standard gastric surgery in each hospital after adjusting for background was observed in the JCOG1001 patients (median, 81%; range, 61%\u201389%). For standard gastric surgery, a higher surgeon volume was significantly but weakly correlated with a higher proportion of patients with postoperative complications (\n                      <jats:italic>\u03c1<\/jats:italic>\n                      \u2009=\u20090.32,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0318). In addition, there were no correlations or trends in the number of dissected lymph nodes, operative time, blood loss volume, 5\u2010year OS, and hospital or surgeon volumes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although there was some degree of interinstitutional variation in short\u2010 and long\u2010term outcomes after standard gastric surgery, we found no correlation between long\u2010term outcomes and hospital or surgeon volumes in JCOG1001.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ags3.70115","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:39:05Z","timestamp":1761626345000},"page":"443-451","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of Hospital and Surgeon Volumes on Clinical Outcomes After Standard Surgery for Advanced Gastric Cancer: Supplementary Analysis of the Multicenter Randomized Phase\n                    <scp>III<\/scp>\n                    Trial\n                    <scp>JCOG1001<\/scp>"],"prefix":"10.1002","volume":"10","author":[{"given":"Motohiro","family":"Hirao","sequence":"first","affiliation":[{"name":"Department of Surgery NHO Osaka National Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2883-0132","authenticated-orcid":false,"given":"Yukinori","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Osaka University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riku","family":"Kajikawa","sequence":"additional","affiliation":[{"name":"Japan Clinical Oncology Group Data Center\/Operation Office National Cancer Center Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junki","family":"Mizusawa","sequence":"additional","affiliation":[{"name":"Japan Clinical Oncology Group Data Center\/Operation Office National Cancer Center Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5057-7985","authenticated-orcid":false,"given":"Kota","family":"Kawabata","sequence":"additional","affiliation":[{"name":"Japan Clinical Oncology Group Data Center\/Operation Office National Cancer Center Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3183-349X","authenticated-orcid":false,"given":"Masanori","family":"Tokunaga","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Institute of Science Tokyo Hospital  Tokyo 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisayuki","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Department of Esophageal and Gastric Surgery Tochigi Cancer Center  Utsunomiya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Takiguchi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Nagoya City University Graduate School of Medicine  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichiro","family":"Doki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Osaka University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1936-9484","authenticated-orcid":false,"given":"Takaki","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Gastric Surgery Division National Cancer Center Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2967-8267","authenticated-orcid":false,"given":"Masanori","family":"Terashima","sequence":"additional","affiliation":[{"name":"Division of Gastric Surgery Shizuoka Cancer Center  Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Stomach Cancer Study Group of Japan Clinical Oncology 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