{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:08:50Z","timestamp":1784297330694,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In lateral lymph node dissection (LLND) for locally advanced or recurrent rectal cancer, concomitant resection of the internal iliac vessels is sometimes required. Because the bladder receives its primary blood supply from branches of the internal iliac artery, concerns arise regarding bladder perfusion when these vessels are resected. However, the extent to which bladder perfusion depends on the internal iliac system remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between 2020 and 2023, 25 patients with locally advanced or recurrent rectal cancer who underwent total pelvic exenteration (TPE) with bilateral LLND were prospectively enrolled. After division of all ventral branches of the internal iliac vessels, including the umbilical, obturator, and vesical vessels, bladder perfusion was evaluated intraoperatively using indocyanine green (ICG) fluorescence imaging. Time to visualization of bladder perfusion was recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bladder perfusion was successfully visualized in all patients without complications. Median time to visualization was 30\u2009s (interquartile range, 20\u201350). Perfusion originated exclusively from the pubic side, and fluorescence of the entire bladder wall was confirmed after mobilization. Patients were classified into early (\u2264 30\u2009s) and delayed (&gt; 30\u2009s) visualization groups. Older age was significantly associated with delayed visualization (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.044), whereas no other clinical or surgical factors showed associations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Bladder perfusion was maintained even after complete interruption of both arterial supply and venous drainage from the internal iliac vessels, owing to blood supply from the pubic side. These findings support the safety of internal iliac vessel resection during extended LLND in rectal cancer surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ags3.70131","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T09:02:15Z","timestamp":1763974935000},"page":"543-547","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative Evaluation of Bladder Perfusion Using Indocyanine Green Fluorescence Imaging During Total Pelvic Exenteration After Interruption of Blood Flow From the Internal Iliac Vessels"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6285-5619","authenticated-orcid":false,"given":"Mamoru","family":"Uemura","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine The University of Osaka  Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1344-7277","authenticated-orcid":false,"given":"Chikako","family":"Kusunoki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine The University of Osaka  Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8814-9792","authenticated-orcid":false,"given":"Mao","family":"Osaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine The University of Osaka  Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kusafuka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine The University of Osaka  Suita 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