{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:39:14Z","timestamp":1792474754502,"version":"4.5.0"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["26AA2006"],"award-info":[{"award-number":["26AA2006"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["26AA2001"],"award-info":[{"award-number":["26AA2001"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Gastroent Surgery"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Although randomized trials have discouraged routine prophylactic abdominal drainage after uncomplicated hepatectomy, these drains are still widely used in clinical practice. This study evaluated the association between prophylactic abdominal drain placement and short\u2010term outcomes after hepatic resection using a nationwide inpatient database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified patients who underwent initial hepatic resection for liver tumors from the Japanese Diagnosis Procedure Combination database. Patients were classified into drain and no\u2010drain groups according to whether a prophylactic abdominal drain was placed intraoperatively. In\u2010hospital outcomes were compared using propensity score overlap weighting. Subgroup analyses were performed for intra\u2010abdominal infection and in\u2010hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 73\u2009613 eligible patients, 62\u2009934 (85.5%) received prophylactic abdominal drains. After overlap weighting, the incidence of intra\u2010abdominal infection did not differ significantly between the drain and no\u2010drain groups (5.1% vs. 5.5%; risk difference, \u22120.3%; 95% confidence interval [CI], \u22120.8 to 0.1). Bile leakage, postoperative transfusion, postoperative drainage, and hospitalization costs were also comparable between groups. In contrast, prophylactic drain placement was associated with lower in\u2010hospital mortality (0.5% vs. 1.0%; risk difference, \u22120.6%; 95% CI, \u22120.8 to \u22120.4). Subgroup analyses showed that this association was more evident in patients with low body mass index and those treated at low\u2010 or middle\u2010volume hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prophylactic abdominal drain placement after hepatic resection was not associated with a lower incidence of intra\u2010abdominal infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ags3.70299","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:02:32Z","timestamp":1792472552000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Prophylactic Abdominal Drain Placement With Short\u2010Term Postoperative Outcomes After Hepatectomy: A Nationwide Inpatient Database Study in Japan"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6433-3184","authenticated-orcid":false,"given":"Keita","family":"Kouzu","sequence":"first","affiliation":[{"name":"Department of Surgery National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7804-2433","authenticated-orcid":false,"given":"Shotaro","family":"Aso","sequence":"additional","affiliation":[{"name":"Department of Health Services Research, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3976-2278","authenticated-orcid":false,"given":"Yuki","family":"Hirano","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary\u2013Pancreatic and Gastrointestinal Surgery International University of Health and Welfare School of Medicine  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Health Economics, School of Public Health The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Health Economics, School of Public Health The University of Tokyo  Tokyo Japan"},{"name":"Center for Next Generation of Community Health Chiba University Hospital  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hiroshima University Hospital  Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Gastroenterological Surgery Sapporo Medical University  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Yamane","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Kawasaki Medical School  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osahiko","family":"Hagiwara","sequence":"additional","affiliation":[{"name":"Department of Surgery Toho University Ohashi Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norikatsu","family":"Miyoshi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine The University of Osaka  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5780-9017","authenticated-orcid":false,"given":"Hiroshi","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Department of Surgery Nippon Medical School Tama Nagayama Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Morikane","sequence":"additional","affiliation":[{"name":"Division of Clinical Laboratory and Infection Control Yamagata University Hospital  Yamagata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichi","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6017-469X","authenticated-orcid":false,"given":"Hideo","family":"Yasunaga","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Health Economics, School of Public Health The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Department of Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8916-4663","authenticated-orcid":false,"given":"Manabu","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Surgery Toho University Ohashi Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2808-4723","authenticated-orcid":false,"given":"Hironori","family":"Tsujimoto","sequence":"additional","affiliation":[{"name":"Department of Surgery National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12322"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12803"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.24576"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-022-06732-5"},{"key":"e_1_2_11_6_1","article-title":"Routine Abdominal Drainage for Uncomplicated Liver Resection","volume":"3","author":"Gurusamy K. 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