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We have trained a U\u2010Net model to utilize baseline OCT to predict the progression of geographic atrophy (GA), a late stage manifestation of AMD. We have augmented the U\u2010Net architecture by attaching deconvolutional neural networks (deconvnets). Deconvnets produce the reconstructed feature maps and provide an indication regarding the inherent baseline OCT features contributing to GA progression. Experiments were conducted on longitudinal spectral domain (SD)\u2010OCT and fundus autofluorescence images collected from 70 eyes with GA. The intensity of Bruch's membrane\u2010outer choroid (BMChoroid) retinal junction exhibited a relative importance of 24%, in the GA progression. The intensity of the inner retinal pigment epithelium (RPE) and BM junction (InRPEBM) showed a relative importance of 22%. BMChoroid (where the AMD feature\/damage of choriocapillaris was included) followed by InRPEBM (where the AMD feature\/damage of RPE was included) are the layers which appear to be most relevant in predicting the progression of AMD.<\/jats:p>","DOI":"10.1002\/ail2.16","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T06:39:24Z","timestamp":1602743964000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Visualizing and understanding inherent features in <scp>SD\u2010OCT<\/scp> for the progression of age\u2010related macular degeneration using deconvolutional neural networks"],"prefix":"10.1002","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5839-8985","authenticated-orcid":false,"given":"Sajib","family":"Saha","sequence":"first","affiliation":[{"name":"Doheny Eye Institute  Los Angeles California USA"},{"name":"Australian e\u2010Health Research Centre CSIRO  Perth Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Doheny Eye Institute  Los Angeles California USA"},{"name":"The University of California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinivas","family":"Sadda","sequence":"additional","affiliation":[{"name":"Doheny Eye Institute  Los Angeles California USA"},{"name":"The University of California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yogesan","family":"Kanagasingam","sequence":"additional","affiliation":[{"name":"Australian e\u2010Health Research Centre CSIRO  Perth Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8307-0298","authenticated-orcid":false,"given":"Zhihong","family":"Hu","sequence":"additional","affiliation":[{"name":"Doheny Eye Institute  Los Angeles California 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