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At birth, three and eight weeks, and six months, secretory cells and duct systems of parotid, submandibular, sublingual and zygomatic glands of mongrel puppies were examined for morphology and localization of sulfomucin, sialomucin, neutral polysaccharide and glycogen. Combining structural and histochemical criteria a classification was formulated to discriminate between mucous, serous, and seromucous cells. Within the first six months of life changes occur in the proportion of these cells in individual salivary glands. Structurally distinct typical and atypical mucous cells contained acidic carbohydrates, usually sulfomucin. In sublingual glands of more mature dogs, however, sialomucin was the predominant constituent in atypical mucous cells. Serous acinar cells containing neutral polysaccharide occurred only in these glands. Seromucous acinar cells secreting acidic carbohydrates, usually sialomucins, were recognized in parotid and zygomatic glands. Demilunes composed of sialomucin\u2010producing seromucous cells and neutral polysaccharide\u2010producing serous cells were observed in submandibular and zygomatic glands, respectively. From this investigation it appears that the structural and carbohydrate profile of developing canine salivary glands is distinctive to the particular age examined.<\/jats:p>","DOI":"10.1002\/aja.1001340308","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T14:26:15Z","timestamp":1109427975000},"page":"377-393","source":"Crossref","is-referenced-by-count":18,"title":["Structure and carbohydrate histochemistry of postnatal canine salivary glands"],"prefix":"10.1002","volume":"134","author":[{"given":"Conrad W.","family":"Reifel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony A.","family":"Travill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"105","article-title":"Observations on the salivary glands of mammals","volume":"2","author":"Bensley R. 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