{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:39:19Z","timestamp":1779291559877,"version":"3.51.4"},"reference-count":56,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,2,3]],"date-time":"2005-02-03T00:00:00Z","timestamp":1107388800000},"content-version":"vor","delay-in-days":6183,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Anat."],"published-print":{"date-parts":[[1988,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The light and electron microscopy of the cervical epithelium of ovulatory, estrous, and long\u2010term ovariectomized rabbits have been studied to determine what structural changes occur under different hormonal conditions. The percentage of nonciliated secretory cells is 49.6 in ovulatory, 43.6 in estrous, and 23.7 in long\u2010term ovariectomized rabbits, and of ciliated cells is 50.2 in ovulatory, 56.2 in estrous, and 76.3 in long\u2010term ovariectomized animals. The values for the ovulatory and estrous rabbits are significantly different at the P &lt;0.05 level from those of the ovariectomized animals.<\/jats:p><jats:p>In all 3 groups the general ultrastructure of the normal ciliated cells is similar. Interestingly, the Golgi complex is very prominent in all. Glycogen bodies occur frequently only in ciliated cells of ovariectomized and occasionally of estrous animals. Abnormalities in cil\u2010iation are quite common in the ovariectomized rabbits.<\/jats:p><jats:p>The structure of the nonciliated secretory cells varies appreciably within and between the 3 groups. In these cells from well\u2010developed epithelia of certain ovulatory and estrous animals, the apical cytoplasm contains secretory granules of at least three types. In addition, very irregularly shaped, dense, perinuclear granules occur, which may be another type of secretory granule or lysosomes. As compared to ciliated cells, the secretory cells have less prominent Golgi complexes, more abundant bundles of intermediate filaments, a more extensive glycocalyx on their apical surface, and more heterochromatic nuclei. In comparison to the cells of well\u2010developed epithelia, the nonciliated cells of some other ovulatory and estrous rabbits are less well differentiated with fewer or no secretory granules and less well developed organelles. In the nonciliated cells of the long\u2010term ovariectomized rabbits, there are no secretory or dense perinuclear granules. There is a decrease in the number of organelles that are involved in secretion, in the size of the cells, and in the amount of nuclear euchromatin.<\/jats:p>","DOI":"10.1002\/aja.1001810307","type":"journal-article","created":{"date-parts":[[2005,2,27]],"date-time":"2005-02-27T02:50:59Z","timestamp":1109472659000},"page":"289-319","source":"Crossref","is-referenced-by-count":10,"title":["Light and electron microscopic observation on the cervical epithelium of the rabbit. I"],"prefix":"10.1002","volume":"181","author":[{"given":"D. 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