{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:02:46Z","timestamp":1760644966023},"reference-count":60,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,2,3]],"date-time":"2005-02-03T00:00:00Z","timestamp":1107388800000},"content-version":"vor","delay-in-days":5116,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Anat."],"published-print":{"date-parts":[[1991,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the rat submandibular gland, the larger ducts, vessels, and AUtonomic elements are surrounded by appreciable collagen to form an extensive, ramifying core for the bulk of the parenchyma. This entity is analogous to the armature within a clay sculpture becAUse it provides a framework supporting softer surroundings. Its largest portion, the trunk, begins dorsorostrally at the hilus. Along its cAUdal course, the trunk emits limbs that, in turn, branch. Rostrally, the trunk and major limbs have their greatest diameters and contain lymphatic vessels and AUtonomic ganglia that are fewer or absent in the smaller divisions. Four to six orders of branching commonly occur. This architectural device constitutes a physical gradient which peaks at the hilus and is minimal where its components undergo the transition to the lobular parenchyma. The presence of an appreciable amount of connective tissue, nerves, and larger vessels would make this entity firmer than the highly hydrated parenchyma. The major divisions of this grouping are contacted by septa that extend from the organ capsule and demarcate lobules into which smaller divisions penetrate. The parenchyma is consequently ensconced between several strong structures containing abundant connective tissue. The dense collagen encompassing individual components of the biological armature would stabilize duct epithelium and its intercellular channels as well as brace vessels' walls. As a result of this architectural arrangement, the patency of all acinar, duct, and vascular structures is likely to persist despite neck and jaw movements that would otherwise distort them and thus hinder the formation and flow of saliva during feeding. This mechanism may be widespread among organs.<\/jats:p>","DOI":"10.1002\/aja.1001900204","type":"journal-article","created":{"date-parts":[[2005,2,27]],"date-time":"2005-02-27T02:18:11Z","timestamp":1109470691000},"page":"133-156","source":"Crossref","is-referenced-by-count":11,"title":["Branchings and course of the larger ducts and accompanying structures within the rat submandibular salivary gland"],"prefix":"10.1002","volume":"190","author":[{"given":"Mortimer","family":"Lorber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"105","volume-title":"Biomechanics. Its Foundations and Objectives","author":"Bergel D. H.","year":"1972"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1976.tb07438.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091940310"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00313028809066618"},{"key":"e_1_2_1_6_1","first-page":"40","volume-title":"Textbook of Cytology","author":"Brown W. V.","year":"1974"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001080304"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(66)90030-2"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-196911000-00027"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1978.58.2.397"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008208309005612"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01964800"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI104849"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(72)90142-0"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1152\/ajplegacy.1964.206.6.1425","article-title":"Mechanical properties of the collagenous framework of skin in rats of different ages","volume":"206","author":"Fry P.","year":"1964","journal-title":"Am. J. Physiol."},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(76)90125-4"},{"key":"e_1_2_1_17_1","first-page":"334","article-title":"Tensile strength and elasticity tests on human fascia lata","volume":"13","author":"Gratz C. M.","year":"1931","journal-title":"J. Bone Joint Surg."},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700880207"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.150.3696.626"},{"key":"e_1_2_1_20_1","first-page":"151","volume-title":"Textbook of Medical Physiology","author":"Guyton A. C.","year":"1991"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1152\/ajplegacy.1962.203.6.1086","article-title":"A technique of studying salivary gland function","volume":"203","author":"Henriques B. L.","year":"1962","journal-title":"Am. J. Physiol."},{"key":"e_1_2_1_22_1","first-page":"127","volume-title":"Sculpture Inside and Out","author":"Hoffman M.","year":"1939"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.48.175"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.36.Suppl_2.63"},{"key":"e_1_2_1_25_1","first-page":"201","article-title":"The post\u2010natal development of the rat submaxillary gland","volume":"93","author":"Jacoby F.","year":"1959","journal-title":"J. Anat."},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01072519"},{"key":"e_1_2_1_27_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1152\/ajplegacy.1930.93.1.353","article-title":"The capillary blood pressure in mammalian mesentery as determined by the micro\u2010injection method","volume":"93","author":"Landis E. M.","year":"1930","journal-title":"Am. J. Physiol."},{"key":"e_1_2_1_28_1","first-page":"316","volume-title":"The Practical Statistician","author":"Linton M.","year":"1975"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1948.02300380051004"},{"key":"e_1_2_1_30_1","first-page":"117","article-title":"Control of resistance, exchange, and capacitance functions in the peripheral circulation","volume":"20","author":"Mellander S.","year":"1968","journal-title":"Pharmacol. Rev."},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1679\/aohc.50.557"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1159\/000145711"},{"key":"e_1_2_1_33_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1161\/01.RES.18.S6.I-3","article-title":"Physical factors which influence vascular caliber and blood flow","volume":"18","author":"Peterson L. H.","year":"1966","journal-title":"Circ. Res."},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.1980.0017"},{"key":"e_1_2_1_35_1","first-page":"223","article-title":"\u00c9tude anatomique des glandes connues sous les noms de sousmaxillaire et sublinguale chez les mammiferes","volume":"18","author":"Ranvier L.","year":"1886","journal-title":"Arch. Physiol."},{"key":"e_1_2_1_36_1","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1152\/ajplegacy.1945.144.4.536","article-title":"Some difficulties involved in the prediciton of the stroke volume from the pulse wave velocity","volume":"144","author":"Remington J. W.","year":"1945","journal-title":"Am. J. Physiol."},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1984.sp002794"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092200304"},{"key":"e_1_2_1_39_1","first-page":"771","volume-title":"Textbook of Physiology","author":"Scher A. M.","year":"1989"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4832-2871-6.50027-8"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(85)90105-0"},{"key":"e_1_2_1_42_1","first-page":"1047","article-title":"Structure of connective tissues, a chemical point of view","volume":"25","author":"Schubert M.","year":"1966","journal-title":"Fed. Proc."},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091690407"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02618428"},{"key":"e_1_2_1_45_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF02889075","article-title":"Morphometric and fine structural study of experimental autoallergic sialadenitis of rat submandibular glands","volume":"28","author":"Sharawy M.","year":"1978","journal-title":"Virchows Arch. [Cell Path.]"},{"key":"e_1_2_1_46_1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3233\/BIR-1974-11407","article-title":"Viscoelastic behavior of conduit arteries","volume":"11","author":"Sharma M. G.","year":"1974","journal-title":"Biorheology"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00398652"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02119776"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.47.030185.001433"},{"key":"e_1_2_1_50_1","series-title":"Symposium on the Mechanism of Exocrine Secretion","first-page":"44","volume-title":"Does transepithelial hydrostatic pressure provide energy for fluid secretion?","author":"Suddick R. P.","year":"1973"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(69)90179-4"},{"key":"e_1_2_1_52_1","first-page":"24","article-title":"Macromolecular aging of collagen. II. The role of water content, solubility and swelling capacity of tendon fibers during aging and storage","volume":"14","author":"Tak\u00e1cs I.","year":"1968","journal-title":"Gerontologia"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1051170303"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5320(63)80036-2"},{"key":"e_1_2_1_55_1","first-page":"8","volume-title":"Salivary Glands and Their Secretion","author":"Tandler B.","year":"1972"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01011900"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1159\/000210714"},{"key":"e_1_2_1_58_1","first-page":"399","volume-title":"Statistical Principles in Experimental Design","author":"Winer B. J.","year":"1971"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00362747"},{"key":"e_1_2_1_60_1","first-page":"105","article-title":"Morphology and physiology of salivary myoepithelial cells","volume":"12","author":"Young J. A.","year":"1977","journal-title":"Int. Rev. Physiol."},{"key":"e_1_2_1_61_1","first-page":"563","volume-title":"Membrane Transport in Biology","author":"Young J. A.","year":"1979"}],"container-title":["American Journal of Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Faja.1001900204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/aja.1001900204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T04:05:29Z","timestamp":1698033929000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/aja.1001900204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,2]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,2]]}},"alternative-id":["10.1002\/aja.1001900204"],"URL":"https:\/\/doi.org\/10.1002\/aja.1001900204","archive":["Portico"],"relation":{},"ISSN":["0002-9106","1553-0795"],"issn-type":[{"value":"0002-9106","type":"print"},{"value":"1553-0795","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,2]]}}}