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However, research on its comprehensive health impacts remains sparse. The study aims to examine the mediating role of health\u2010risk behaviors (HRB) and the moderating role of social support in the relationship between FDV and HRQoL. Data were drawn from the 2022 Psychology and Behavior Investigation of Chinese Residents, involving 4003 adolescents aged 12\u201319 years in China. Structural Equation Models were employed to investigate the relationship between FDV, HRB, social support, and adolescent HRQoL. Nearly half of the adolescents reported experiencing FDV. FDV was significantly associated with lower HRQoL among adolescents. HRB, such as smoking, alcohol consumption, sleep disorders, and appetite loss, mediated this relationship. Social support moderated the effects of HRB on HRQoL, buffering the negative impact. Gender differences were observed in how specific types of FDV affected HRQoL. These results provide a basis for policymakers to develop comprehensive strategies for reducing HRB and strengthening support systems for adolescents. Additionally, gender\u2010specific interventions are essential for addressing the unique needs of affected populations.<\/jats:p>","DOI":"10.1002\/ajcp.70059","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T11:11:35Z","timestamp":1773832295000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of family and domestic violence on adolescents' health\u2010related quality of life in China: Roles of health\u2010risk behaviors and social supports"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0255-8847","authenticated-orcid":false,"given":"Siyuan","family":"Liu","sequence":"first","affiliation":[{"name":"Population Development Studies Center, School of Population and Health Renmin University of China Beijing China"},{"name":"Institute of Health Sciences, School of Population and Health Renmin University of China Beijing China"},{"name":"Big Data and Responsible Artificial Intelligence for National Governance Renmin University of China Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3084-9390","authenticated-orcid":false,"given":"Yueping","family":"Song","sequence":"additional","affiliation":[{"name":"Population Development Studies Center, School of Population and Health Renmin University of China Beijing China"},{"name":"Institute of Health Sciences, School of Population and Health Renmin University of China Beijing China"},{"name":"Big Data and Responsible Artificial Intelligence for National Governance Renmin University of China Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8401-288X","authenticated-orcid":false,"given":"Zhixin","family":"Shi","sequence":"additional","affiliation":[{"name":"Population Development Studies Center, School of Population and Health Renmin University of China Beijing China"},{"name":"Institute of Health Sciences, School of Population and Health Renmin University of China Beijing China"},{"name":"Big Data and Responsible Artificial Intelligence for National Governance Renmin University of China Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7525-4473","authenticated-orcid":false,"family":"Chenyu Yan","sequence":"additional","affiliation":[{"name":"Vanke School of Public Health Tsinghua University Beijing China"},{"name":"Institute for Healthy China Tsinghua University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9607-313X","authenticated-orcid":false,"given":"Yibo","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Nursing, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine Zhejiang University Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"issue":"3","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1002\/1097-0142(19910201)67:3+<839::AID-CNCR2820671415>3.0.CO;2-0","article-title":"Quality of life research in oncology: Past achievements and future priorities","volume":"67","author":"Aaronson N. 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