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Therefore, this study explores how adolescent perceptions of structural and social community risk factors are associated with lifetime and past 30\u2010day use of alcohol, marijuana, cigarettes, and illicit drugs among adolescents in different geographic locations. Data from 9819 adolescents from the 2019 Florida Youth Substance Abuse Survey were used to estimate associations between adolescent perceptions of community risk factors and lifetime and past 30\u2010day alcohol, marijuana, cigarette, and illicit drugs using logistic regression models stratified by geographic location. Adolescent perceptions of community disorganization were significantly associated with lifetime and past 30\u2010day alcohol use among town and rural adolescents and illicit drug use among adolescents from all geographic locations. 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