{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:45:03Z","timestamp":1790419503833,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2002,5,29]],"date-time":"2002-05-29T00:00:00Z","timestamp":1022630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2002,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of spontaneous gas gangrene (SGG), the most rapidly progressive form of clostridial infection, in a patient with non\u2010Hodgkin's lymphoma (NHL). We review the literature and examine the association between these two entities. A 43\u2010year\u2010old man with NHL developed fatal <jats:italic>C. perfringens<\/jats:italic>\u2010associated SGG and massive hemolysis during induction chemotherapy. Although patients with NHL usually have several risk factors of SGG, such as bowel involvement or neutropenia, only two cases have been described previously in detail. Common features of all reports are a delayed diagnosis and a fatal outcome. Awareness of this condition should result in prompt antibiotic therapy at the onset of typical presenting symptoms in any lymphoma patient, especially if risk factors are present. Am. J. Hematol. 70:145\u2013148, 2002.\u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.10106","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T12:35:39Z","timestamp":1033907739000},"page":"145-148","source":"Crossref","is-referenced-by-count":17,"title":["Spontaneous gas gangrene in malignant lymphoma: An underreported complication?"],"prefix":"10.1002","volume":"70","author":[{"given":"Julio","family":"Garc\u00eda\u2010Su\u00e1rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dunia de","family":"Miguel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Krsnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Barr\u2010Al\u00ed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Hernanz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Burgaleta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,5,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197804)41:4<1610::AID-CNCR2820410452>3.0.CO;2-B"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910401)67:7<1928::AID-CNCR2820670718>3.0.CO;2-9"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005200050146"},{"key":"e_1_2_1_5_2","first-page":"2182","volume-title":"Principles and practice of infectious diseases","author":"Lorber B","year":"1995"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/10.2.347"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90018-X"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198910000-00018"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1994.tb02291.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02962255"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/12.2.286"},{"key":"e_1_2_1_12_2","first-page":"5432","article-title":"Non\u2010Hodgkin's lymphoma time trends: United States and International data","volume":"52","author":"Devesa SS","year":"1992","journal-title":"Cancer Res"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(98)00401-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(97)90088-7"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(90)90538-O"},{"key":"e_1_2_1_16_2","first-page":"571","article-title":"Massive hemolysis in Clostridium perfringens infection","volume":"84","author":"Alvarez A","year":"1999","journal-title":"Haematologica"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.3.1.66"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/155.2.220"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.3109\/07357909509024913"},{"key":"e_1_2_1_20_2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.5858\/2000-124-0353-TROCSI","article-title":"The role of Clostridium septicum in paraneoplastic sepsis","volume":"124","author":"Pelletier JP","year":"2000","journal-title":"Arch Pathol Lab Med"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.10106","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.10106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T10:03:23Z","timestamp":1700301803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.10106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5,29]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,6]]}},"alternative-id":["10.1002\/ajh.10106"],"URL":"https:\/\/doi.org\/10.1002\/ajh.10106","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,5,29]]}}}